OBJECTIVE The optimal target for glycemic control has not been established in diabetic dialysis patients. RESEARCH DESIGN AND METHODS To address this question, the national database of a large dialysis organization (DaVita) was analyzed via time-dependent survival models with repeated measures. RESULTS Of 82,933 patients undergoing maintenance hemodialysis (MHD) in DaVita outpatient clinics...

Patients with diabetes mellitus are at risk for developing severe debilitating complications, including retinopathy, nephropathy, neuropathy, myocardial infarction, and stroke. Randomized trials have documented that lowering hemoglobin A1c (Hb A1c) 4 concentrations significantly reduces the onset and rate of progression of microvascular complications (1, 2 ). Moreover, Hb A1c, which is formed b...