Coombs' positive hemolytic anemia is exceedingly rare in tuberculosis. We herein report a patient with tuberculosis associated with Coombs' positive hemolytic anemia that was responded to antituberculosis therapy. She was admitted to the hospital because of recent-onset fatigue, weakness, nonproductive cough, pallor and scleral jaundice. Coombs positive hemolytic anemia and pulmoner tuberculosi...

Warm antibody autoimmune hemolytic anemia is due to the presence of warm agglutinins that react with protein antigens on the surface of red blood cells causing premature destruction of circulating red blood cells. We report the first case of concurrent reactive arthritis, Graves' disease, and autoimmune hemolytic anemia. A 40-year-old man with reactive arthritis, Graves' disease, type 2 diabete...

the most common form of acquired hemolytic anemia is associated with what appears to be autologous igg hemagglutinins. these anti-bodies may arise unexpectedly and in the absence of any recognizable underlying disease. however, they are observed not uncommonly as a complication of systemic lupus erythematosis, chronic lymphatic leukemia, lymphosarcoma, ulcerative colitis, etc. 'the red cells of...

glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most prevalent enzymopathy in mankind. it has sex-linked in­heritance. this enzyme exists in all cells.  g6pd deficiency increases the sensitivity of red blood cells to oxidative dam­age. g6pd deficiency was discovered in 1950 when some people suffered hemolytic anemia as a result of taking antimalar­ial drugs (primaquin). most people w...

Bendamustine is an alkylating agent approved for the treatment of chronic lymphocytic leukemia (CLL) and B-cell non-Hodgkin lymphoma. There are scant reports on bendamustine-induced immune hemolytic anemia occurring mainly in CLL patients. We report a case of immune hemolytic anemia that developed after exposure to bendamustine in a 70-year-old female with CLL who was previously exposed to flud...

(Case 1) A 13-years-old female had multiple arthralgia and butterfly rush, when she admitted in our hospital in May 2001. Nephropathy, hemolytic anemia (Hb 6.3 g/dl and direct Coombs 3+) and high titers of antinuclear antibodies and anti-ds-DNA antibody were disclosed and she was diagnosed as systemic lupus erythematosus (SLE). Although combination therapy of PSL 60 mg/day with a steroid pulse ...

REFERENCES 1. Mayer B, Yurek S, Kiesewetter H, Salama A. Mixed-type autoimmune hemolytic anemia: differential diagnosis and a critical review of reported cases. Transfusion 2008;48:2229-34. 2. Sudha Reddy VR, Samayam P, Ravichander B, Bai U. Autoimmune hemolytic anemia: mixed type-a case report. Indian J Hematol Blood Transfus 2011;27:107-10. 3. Hoffman PC. Immune hemolytic anemia-selected topi...

I N 1949, Owren first noted a beneficial effect of heparin therapy in autoimmune hemolytic anemia.1 Dramatic therapeutic responses were subsequently reported by other investigators.26 However, neither the value nor the precise mechanism of action of this drug has been elicited in the treatment of autoimmune hemolytic anemia. We have evaluated the use of parenteral heparin in seven patients with...

hemolytic anemia is exceedingly rare and an underestimated complication after aortic valve replacement (avr).the mechanism responsible for hemolysis most commonly involves a regurgitated flow or jet that related to paravalvar leak or turbulence of subvalvar stenosis. it appears to be independent of its severity as assessed by echocardiography. we present a case of a 24-year-old man with a histo...