the purpose of these case reports is to analyze the results of gingivectomy and gingival troughing to determine the evidence on the effectiveness of laser-assisted soft tissue procedures and soft tissue management in aesthetic dentistry.the patients in these case reports underwent 980 nm diode laser assisted gingivectomy and gingival troughing to achieve immediate hemostasis and moisture contro...

A wide range of orthopedic, cardiothoracic, neurological, and maxillofacial procedures requires that the bone be cut or resected, either to operate on the osseous tissue itself or to gain access to other organs. As any living tissue, bone bleeds when cut or fractured, and to reduce the risk of post-operative complications, bone bleeding needs to be managed during surgery. The present chapter ex...

Fibronectin (Fn) is an essential extracellular matrix protein involved in cell adhesion, migration, differentiation and proliferation. Fn is required for embryogenesis, and is intricately involved in malignant transformation, angiogenesis, inflammation, fibrosis, wound healing, thrombosis and hemostasis [1]. Fn is a dimer consisting of two 250 kDa subunits. Alternative splicing of Fn pre-mRNA a...

Topical, local, regional, and systemic routes of medication administration have been employed for preventing or reducing blood loss and associated transfusion requirements in patients with bleeding diatheses. Examples would include topical fibrinor thrombin-based products for wound hemostasis, proton pump inhibitor therapy for preventing gastric rebleeding in patients with peptic ulceration, oc...

Microfibrillar collagen hemostat (MCH) is accepted as an effective topical hemostatic agent during endoscopic endonasal transsphenoidal surgery (EETS), particularly to achieve venous hemostasis; however, handling MCH may be troublesome because of its adherence to gloves and instruments. We describe here a method of "injection" of MCH suspension using a syringe applicator. This technique allows ...

Hemostasis must be accurate in laparoscopic surgery because it is vital to extirpative and reconstructive procedures. Even small amounts of hemorrhage can negatively influence the efficiency and safety of any procedure. In addition to physically obscuring anatomic structures, hemorrhage—even modest amounts—can darken the surgical field, reducing reflection of light and, therefore, visibility. D...

Welcome to another of our Eberhard F. Mammen Award announcements. As noted previously,1–3 Thieme, the publisher of Seminars in Thrombosis & Hemostasis, has created the “Eberhard F. Mammen Excellence in Thrombosis and Hemostasis Awards” in honor of Eberhard Mammen (►Fig. 1) and in recognition of his contribution to this field and to the journal that he founded and steered for over three decades....

OBJECTIVE Post-tonsillectomy hemorrhage remains an important factor in determining the safety of performing tonsillectomy as a day case procedure. The aim of this study was to determine the safety of day case tonsillectomy by using combination method, cold dissection tonsillectomy and bipolar diathermy hemostasis. METHODS A prospective randomized clinical study conducted on the patients who h...

BACKGROUND Bleeding time has been used for a long time as a global test of platelet function. Due to a number of pitfalls the test has been losing popularity. This study was designed to determine the prevalence of prolonged bleeding time in Nigerians with chronic liver disease in relation to other indices of hemostasis. METHODS Bleeding time, platelet count, prothrombin time (PT) and activate...

Recently, our laboratory showed that platelets, like leukocytes, roll on activated endothelium expressing P-selectin, thus suggesting a role for P-selectin in hemostasis (Frenette et at, Proc Natl Acad Sci USA 92:7450, 1995). We report here that the P-selectin--deficient mice show a 40% prolongation of the bleeding time on amputation of the tip of the tail. Moreover, defective hemostasis was ob...