We explored the protective effect of ischemia preconditioning (IP) on ischemia-reperfusion injury in rat liver transplantation. An orthotopic liver transplantation model was utilized in the study. A total of 54 Sprague-Dawley rats were divided into a control group (group A, no liver transplantation), liver transplantation group (group B, heparin Ringer's lactate solution was perfused via the po...

Polycystic liver disease, commonly associated with polycystic kidney disease, can result in massive hepatomegaly and debilitating symptoms. Surgical intervention for symptomatic polycystic liver disease has been associated with significant morbidity and inconsistent long-term palliation; it is more appropriate in patients with a single dominant cyst or cysts which is/are confined to one lobe. A...

Congenital Hepatic Fibrosis (CHF) is a rare disease that affects both the liver and kidneys.  Congenital hepatic fibrosis (CHF) is an autosomal recessive inherited malformation defined pathologically by a variable degree of periportal fibrosis and irregularly shaped proliferating bile ducts. Affected individuals also have impaired renal function, usually caused, in children and teenagers, by an...

Pseudoaneurysm (PA) of the hepatic artery is a rare complication abdominal trauma, iatrogenic injuries (biopsy, endoscopic cholecystectomy, liver transplantation), infections, tumors, vasculitis, acute and chronic pancreatitis. This case report presents life-threatening complications in patient who underwent surgery for lesion. Due to use CT angiography, it was possible determine cause bleeding...

Abstract Hepatocellular carcinoma (HCC) recurrence after liver transplantation remains a significant clinical problem. Ischemia-reperfusion injury (IRI) occurred inevitably at the early phase (LT) spawns risk of HCC recurrence. However, their linkage and IRI-derived factors for remain exclusive. Understanding mechanism post-transplantation hepatic could provide new strategies to prevent later e...

Background. An adequate blood flow is directly related to graft survival in living donor liver transplantation. However, in some cases, unfavorable conditions prevent the use of the hepatic artery for arterial reconstruction. Herein, we report a case in which the recipient right gastroepiploic artery was used as an option for arterial reconstruction in adult-to-adult living donor liver transpla...

FAP is an autosomal dominant inherited disease, characterized by systemic deposition of amyloid fibrils in various tissues. The purpose of this study is to describe the gross and microscopic findings of the explanted livers for FAP.10 patients were transplanted for FAP at our institution. Diagnosis was supported by positive familiar history, clinical data and detection of mutated TTR by electro...

The treatment of choice for hepatic malignancy has been total surgical removal of tumor(s). Extensive liver resect..ion such as right and left trisegmentectomies can now be performed with an operative mortality ofless than 5% [I). Five-year survival of primary liver malignancy after suhtotal liver resection has heen as high as 46% [I]. On the other hand, the prognosis of liver cancer which cann...

OBJECTIVE To evaluate the frequency and outcome of liver transplantation for symptomatic, unresectable, benign hepatic neoplasms. DESIGN Retrospective study. SETTING Presbyterian University Hospital, a tertiary care referral center for liver transplantation affiliated with the University of Pittsburgh (Pa). PATIENTS All 3239 liver transplant recipients at the University of Pittsburgh from...