Liver disease, particularly viral hepatitis, is increasingly common. The most frequent causes of long-term, or chronic, viral hepatitis are persistent infections with the hepatitis B or hepatitis C virus. Worldwide, 400 million people are chronic carriers of the hepatitis B virus [1]. Each year, between 500,000 to 1.2 million people die from progression of this viral infection, making it the 10...

methods and materials: hepatitis b virus dna was detected by conventional pcr in some of the serum samples obtained from hbsag-positive chronic hepatitis b (chb) patients who were referred to health centers of shahrekord for routine monitoring of the disease. subsequently, using real-time pcr, the dna samples were used for genotyping and analysis of resistance to lamivudine. results: the dna wa...

OBJECTIVE To determine peroxisome proliferator activated receptor α and γ mRNA expression in liver tissue of hepatitis C virus-infected patients with and without human immunodeficiency virus and its possible contribution to an acceleration of liver disease progression. METHODS We measured peroxisome proliferator-activated receptor α and γ mRNA expression by real-time polymerase chain reaction...

Hepatitis C virus infects over 15 million patients from India and 2.86 million from Brazil. Detection of anti-hepatitis C virus antibodies has limited sensitivity during acute phase: the pre-seroconversion window period. Hepatitis C virus-RNA detection techniques are used to overcome this shortfall, but are costly and unavailable widely in developing countries. Estimation of hepatitis C virus c...

hepatitis c virus (hcv) has infected 3% of the population worldwide and 20% of the population in egypt. hcv infection can lead to hepatocellular carcinoma and death. the presently available treatment with interferon plus ribavirin, has limited benefits due to adverse side effects. seaweeds have become a major source of new compounds to treat viral diseases. this work aimed to study the effect o...

background chronic hepatitis c virus (hcv) is associated with extra hepatic autoimmune disorders, while peg-ifna-2a/rbv combination therapy may exacerbate these conditions. autoantibodies to cytoplasmic structures, called rod and ring particles (rr), have strong associations with these patients and are identified by hep-2 cells. objectives our purpose was to study the correlation of autoantibod...

'die presence anil significance of hepatitis c virus infection among patients with chronic renal failure (crf) on hemodialysis and renal transplant recipient were evaluated a pcrioil of 30 months. a total of 125 patients, comprising 25 recieving chronic hemodialysis, 47 renal transplant candidates and 5.1 renal transplant recipients, were studied with a second generation immunoassay (elisa ii)....

conclusions the high prevalence of hcv infection among this group implies a high rate of transmission and exposure to the risk of serious diseases. it is important that the high prevalence of hcv infection be taken into consideration to control further transmission of this infection. background hepatitis c is an infectious disease caused by blood-borne pathogen, hepatitis c virus (hcv). objecti...

objectives the aim of this study was to investigate the possible associations between co-stimulatory molecule gene polymorphisms and viral infections in kidney transplant patients. results cmv active infection was found in 31 of 172 (18.02%) kidney transplant patients. hcv infection was only found in two of the 172 (1.16%) studied patients. significant associations were found between tt and tc ...