objectives in the current case control study, we aimed to compare the histopathological findings of liver to the ccr5δ32 bpdel mutation profiles, expression and some other clinical findings in patients with chronic hcv infection. background the specific antiviral t cells provide cc chemokine receptor 5 (ccr5) for the immune response during the hepatitis c virus (hcv) infection. heterogenous and...

this study was conducted to find out the prevalence, viral load and co-infection of hbv and hcv infection among patients seeking to hospital care in mashhad, iran. a total of 402 samples (349 samples for hbv and 53 for hcv) were received and were screened for hepatitis b and c during 2004 to 2014. viral loads of hbv dna and hcv rna were quantified by real-time pcr. among 349 collected samples, ...

conclusions the prevalence of hbv infection among donors in duhok was comparable with those of reports from other parts of iraq. education and immunization should be initiated to target the high-risk groups. furthermore, a community-based study is recommended to study the prevalence of hbv and hcv infection in the population. background the prevalence of blood borne viral infection is escalatin...

background: hepatitis g virus (gbv-c) is a single strand rnapositive virus and is a member of flaviviridae family. infection with the virus is prevalent add has worldwide distribution. accurate diagnosis of the virus is very important, because of co-infection with other important viruses like hcv, hbv and hiv, it may influence on pathogenesis, disease progression and response to viral therapy. ...

conclusions the results of this study revealed the important role injection drug use plays as the main cause of hcv spread in isfahan province. effective harm reduction programs should be implemented to prevent new hcv infections. considering the high prevalence of hcv infection among hiv patients, this group should receive special attention. results twenty-eight studies, including 6, 17, 4, an...

results the study found that 72 patients, 43 males and 29 females, had documented hcv infections. age’s ranged from 20 - 75, with a mean of 48. the largest number of patients had the 1a genotypes (41 patients = 56.9%), followed by 3a (25 patients = 34.7%), and 1b and 4a each of them (3 patients = 4.2%). conclusions the study showed that genotypes 1a and 3a are the most common genotypes in patie...

background and objectives: hepatitis c virus (hcv) infection is a worldwide concern and it is the major cause of liver disease. several genotypes of the hcv have been reported from different regions of the world. the determination of the hcv genotypes is important for the prediction of response to antiviral treatment and clinical outcomes. so, hcv genotyping in each region is of great importanc...

results in patients with an svr, the serum levels of aminotransferases were decreased after hcv eradication. although general liver functional tests (albumin and total bilirubin) did not significantly change, the btr values significantly increased. however, in patients without an svr, an improvement in the btr value was not observed after ifn treatment. conclusions hcv eradication can improve t...

conclusions it is suggested that determination of the target genotype by plasma subtyping for choosing the proper antiviral therapy is essential but may result in therapy failure. hcv genotyping in pbmc samples, along with plasma specimens, might be more beneficial. therefore determining the hcv genotype in pbmcs, before beginning the therapy is useful due to the possibility of occult infection...

background: hepatitis c (hcv) is increasing worldwide including iran. hcv is more prevalent among intravenous drug abusers (idu), especially if imprisoned, mostly due to needle sharing. we determined the rate of hcv seropositivity among idu prisoners and compared it with those of non prisoners. materials and methods: a cross-sectional survey was done on consenting idu inhabiting two prisons and...