The effect of crude lysate of Chlorella sp. (CLC) on acetaminophen (APAP)-induced liver injury in male ICR mice was investigated. The CLC is a protein-enriched powder containing around 65% of microalgal proteins. There were no hepatotoxicity and renal toxicity detected in the mice fed with the feed containing CLC with a much high level of 10% for 28 days. The hepatoprotective function of CLC wa...

Antrodia cinnamomea CHANG TT & WN CHOU (Chinese name, niu-chang-chih or niu-chang-ku; synonym Antrodia camphorata WU SH et al.) is a new species of the genus Antrodia (family polyporaceae, Aphyllophorales) that is parasitic on the inner cavity of the endemic species Cinnamomum kanehirai HAY. This endangered species has been used in Taiwan to treat food, alcohol, and drug intoxication, diarrhea,...

Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for liver injury.The present study was conducted to evaluate the hepatoprotective activity of aqueous ethanolic extract of aerial parts of Basella rubra in wistar rats. The studies were conducted using the two popular inducing agents Paracetamol (2gm/kg,p.o.) in 1% CMC and Carbon tetrachloride (...

In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...

Several human diseases including, cancer, rheumatoid arthritis, neurodegenerative and hepatic diseases are related to destructive effect of reactive oxygen species (ROS). Antioxidants may provide a possible solution to this problem.This study was carried out to investigate the effect of hydroalcoholic extract of Celtis australis on CCl4 induced hepatotoxicity in mice.  The antioxidant activity...

Lepidium sativum seed (LSS) (family: Cruciferae) has been used in traditional medicine for the treatment of jaundice, liver problems, spleen diseases and gastrointestinal disorders. It was also reported to possess antihypertensive, diuretic, anti-asthmatic, antioxidant, and anti-inflammatory activities. Attempt has been made to study hepatoprotective potential of LSS available in Saudi Arabian ...

BACKGROUND Coreopsis tinctoria is a traditional remedy for the management of various diseases including hepatitis. The hepatoprotective role of the plant is not scientifically explored till now. This study was designed to investigate the hepatoprotective potentials of the ethanol extract from C. tinctoria (CTEtOH) using an animal model of carbon tetrachloride (CCl4)-induced acute liver injury. ...