e72 Volume 35 Number 8S in severely obese diabetic patients having BS versus conventional/intensive antidiabetic therapy. Respectively, in these trials: patient numbers were 60 and 150, primary end points were 2-year HBA1C level ≤6.5% (with fasting glucose < 100 mg/dL and no anti-DM pharmacotherapy) and 1-year HBA1C levels ≤6%, and surgical interventions were gastric bypass and bilio-pancreatic...

This study was designed to determine the antioxidant and hepatoprotective effect of nbutanol soluble fractions of Albizzia lebbeck The various extracts were prepared and extracts containing flavanoids, tannins and saponins (Methanolic extract) was selected for isolation of chemical constituents. nbutanol soluble fractions of extract (BFALB) and leaf extract (BFALL) were selected for screening o...

Dendrobium huoshanense is a precious herbal medicine in China, which exhibits a variety of restorative and therapeutic effects. This study aimed at investigating the hepatoprotective effects of a polysaccharide (DHP1A) isolated from D. huoshanense via water extraction, diethylaminoethyl (DEAE) cellulose anion exchange and size exclusion chromatography. The animal experiment indicated that the o...

The study was undertaken to investigate the hypolipidemic and hepatoprotective effects of the different fractions (Petroleum ether, ethyl acetate and chloroform) of ethanolic extract of immature leaves of Mangifera indica. The different fractions of extract were administered intraperitonially as a single dose of 150 mg/kg body weight to alloxan induced diabetic rats and found to reduce blood li...

the present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methanol extract of eupatorium ayapana (meea) (family- asteraceae) leaves in wistar albino rats. the different groups of animals were administered with carbon tetrachloride (ccl4) at 72 h interval.  the meea at 100, 200 and 300 mg/kg and silymarin 25 mg/kg were administered to the ccl4 treated rats....

Oral pre-treatment with ethanolic extract of the roots of C. carandas (ERCC; 100, 200 and 400 mg/kg, po) showed significant hepatoprotective activity against CCl4 and paracetamol induced hepatotoxicity by decreasing the activities of serum marker enzymes, bilirubin and lipid peroxidation, and significant increase in the levels of uric acid, glutathione, super oxide dismutase, catalase and prote...

OBJECTIVE To evaluate the hepatoprotective potential of Hepax, a polyherbal formulation, against three experimentally induced hepatotoxicity models in rats. METHODS Hepatoprotective activity of Hepax was studied against three experimentally induced hepatotoxicity models, namely, carbon tetrachloride (CCl4), paracetamol and thiocetamide induced hepatotoxicity in rats. RESULTS Administration ...

mammea africana sabine (guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. the hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, to...

In male Wistar rats the hepatoprotective effect of pollen extracts (Cernitins) agains. orally introduced 1% allyl alcohol (0.4 ml per 100 g body weight) was investigated Cernitins were applied orally at 0.6, 24 and 30 h after allyl alcohol administration. After 48 h an autopsy was performed and blood was collected for biochemical tests. Liver damage was evaluated by measurement of aminotransfer...