A high-performance liquid chromatographic (HPLC) analysis of triterpenoids from Ganoderma is developed and validated in an attempt to explore a way to differentiate a number of species of the genus Ganoderma. Results show that 64 samples examined in this study could be divided into 18 groups based on characteristics of the HPLC pattern of triterpenoids. This result also conforms with those of t...

Two triterpenoids ursolic acid (1) and lupeol (2) isolated and characterized from Eucalyptus tereticornis and Gentiana kurroo were subjected to in silico QSAR modeling and docking studies and later the predicted results were confirmed through in vivo experiments. QSAR modeling results showed that both the triterpenoids possess immunomodulatory and anti-inflammatory activity comparable to boswel...

Ganoderma lucidum is generally called “Lingzhi or Reishi”, and also be a Traditional Chinese medicine utilized in over 2000 y for their better therapeutic activity like antitumor, antiallergenic, antiviral, hepatoprotective, antioxidant, hypotensive, immunomodulator, hypoglycemic, anti-inflammatory, antithrombotic, antibacterial many other health benefits. one of the oldest herbal remedy found ...

Triterpenes are group of biologically active compounds which can be found in higher plants. Their main source are plants bark, leaves, twigs, fruits, resins or oils. The biological activity of triterpens is very diversified and many studies have already confirmed the following therapeutic effects: anti-inflammatory, antimicrobial, antiviral, antifungial, immunomodulatory, and hepatoprotective. ...

Apocynaceae is a large family of tropical trees, shrubs and vines with most species producing white latex. Major metabolites of species are triterpenoids, iridoids, alkaloids and cardenolides, which are known for a wide range of biological and pharmacological activities such as cardioprotective, hepatoprotective, neuroprotective, anti-inflammatory, anticancer and antimalarial properties. Prompt...

The practice of plants for the deterrence and management innumerable physiological states diseases dates back to history humankind. Although many today’s medicinal yields are achieved synthetically, they often modelled on chemical composition plants. In this accordance, Acanthus genus (Family Acanthaceae) has acknowledged considerable attention due its wide range secondary metabolites customary...

Since times immemorial, plants are considered as an important source for the treatment of a wide range diseases. Herbal medicine is study pharmacognosy and use medicinal plants, which basis traditional medicine. These herbal therapies cost effective free from any side effect. Although there around 8,000 plant species used by different communities in India across ecosystems, only 10% them (880 s...

Toona ciliata is the plant mainly distributed in sub Himalayan tract. Traditionally, it is useful in chronic dysentery, leprosy, cures fever, headache, blood complaints, cardiotonic, aphrodisiac, and ulcer. Toona ciliata is traditionally used in menstrual disorders. The phytoconstituents present in the plants including triterpenoids, cedrelone, polyynes, limonoids, siderin, steroids etc. Pharma...

Several oleanane-related triterpenoids bearing a unique C-2 oxygenated functionality have been identified as the predominant triterpenoids from a 4900 year old oak wood sample buried in a freshwater sediment. They likely represent specific molecular tools that can be used as markers to reconstruct past vegetation assemblages, or to recognise severely altered oak wood at archaeological sites.

For the development of novel hepatoprotective agents, C2, C3, C23 and C28 functional groups on asiatic acid were modified, and the prepared compounds were evaluated for their hepatoprotective effects. Among the prepared compounds, 9, 13 and 16 showed significant hepatoprotective activities against CCl4and galactosamine (GaIN)-induced hepatotoxicity. Especially, compound 9 showed the most signif...