Background: Breast cancer (BC) has now surpassed lung as the leading cause of global incidence in 2020, with an estimated 2.3 million new cases, representing 11.7% all cases. It is a highly heterogeneous disease variety morphologic and clinical manifestations which results range responses to treatment. Recently, targeted therapies based on genetic, hormonal, or immunohistochemical (IHC) subtype...

breast cancer is the most common cancer in women except skin cancer. the common metastatic sites include lymph node, lung, liver and bone. however, metastasis to the bladder is extremely rare. to our knowledge, this is the first case of breast cancer metastasis to urinary bladder in jordan which is reported. nine years after the initial diagnosis of lobular breast carcinoma, the patient suffere...

Relevance: Male breast cancer (BC) is one of the rarest diseases and accounts for 1/100 detected BC cases in both sexes. About
 30-70% men develop against background gynecomastia, particularly its nodular form. The biology this
 disease differs men, but approaches to diagnostics treatment are usually extrapolated from those used women.
 This study aimed demonstrate results each s...

BACKGROUND To assess the immunohistochemical expression of estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor-2 (HER2) neu receptor in breast cancer and their associations with various clinicopathological characteristics. MATERIALS AND METHODS This is a retrospective analysis of women who presented with primary, unilateral breast cancer in the Depar...

Abstract Leptomeningeal disease (LMD) in breast cancer carries a poor prognosis with median overall survival (OS) of 3-4 months. Recent series have indicated prolongation OS up to 10-13 months HER2-positive LMD treated intrathecal (IT) trastuzumab. Here we present an unprecedented long-term clinical, radiographic, and molecular response for more than 10 years on IT A 52-year-old woman presented...