Chronic pain represents a major problem in clinical medicine. Whilst the acute pain that is associated with tissue injury is a protective signal that serves to maintain homeostasis, chronic pain is a debilitating condition that persists long after the inciting stimulus subsides. Chronic neuropathic pain that develops following damage or disease of the nervous system is partially treated by curr...

objective(s):neuropathic pain is caused by lesions or diseases affecting the somatosensory system and often responds poorly to typical medications.  in this study, we evaluated anti-nociceptive effects of morphine, gabapentin and their combination on heat hyperalgesia, cold and mechanical allodynia in chronic constriction injury (cci) model of neuropathic pain in rats. materials and methods: mo...

Received: November 12, 2008. Accepted: January 30, 2009. Corresponding author: Yeon Soo Jeon, M.D., Department of Anesthesiology and Pain Medicine, St. Vincent Hospital, The Catholic University of Korea, College of Medicine, 93-6, Ji-dong, Paldal-gu, Suwon 442-723, Korea. Tel: 82-31-249-7273, Fax: 82-31-258-4212, E-mail: [email protected] Copyright c Korean Society of Anesthesiologist...

Neuropathic pain represents a major problem in clinical medicine because it causes debilitating suffering and is largely resistant to currently available analgesics. A characteristic of neuropathic pain is abnormal response to somatic sensory stimulation. Thus, patients suffering peripheral neuropathies may experience pain caused by stimuli which are normally nonpainful, such as simple touching...

Cancer patients suffer from physical pain due to cancer itself and side effects by anticancer drugs, as well social such employment problems, psychological spiritual pain. It is important overcome these total pains with multidisciplinary medical care. Regarding drug treatment, if there no effective in alleviating the patients' symptoms, it necessary develop a novel or repositioning apply existi...

background: the increase in the use of herbal products is noticed all over the world. the safety of herbal drugs becomes particularly important in pregnant women and children. despite the fact that available data are insufficient to justify herbal use during pregnancy, exposure to herbal products is frequent in these subjects. some of the more complex reasons for preference of herbal medicine a...

conclusions this study showed the efficacy of m. longifolia in relieving pds symptoms and improving the qol of patients with pds. results at the end of treatment period, the m. longifolia group reported a more significant improvement in the mean severity scales of fd symptoms than the placebo group (p < 0.001). a significant difference was also observed between fd symptoms and severity scores i...

discussion while this novel type of drug delivery is known as a suitable substitute for oral and parenteral administration, it was well accepted and extensively mentioned in persian medical and pharmaceutical manuscripts and other traditional systems of medicine as well. accordingly, medieval pharmaceutical standpoints on nasal dosage forms could still be an interesting subject of study. theref...

context functional dyspepsia (fd) is a functional gastro-intestinal disorder with high prevalence. among various treatment options, treatment by complementary and alternative medicines especially herbal remedies also practiced. traditional iranian medicine (tim), a valuable resource of valid applied studies of ancient iranian scholars, recommends numerous medicinal plants to treat dyspepsia sym...

BACKGROUND Reflex sympathetic dystrophy (RSD) is a serious and potentially disabling condition and is a very complex syndrome, which consists of pain maintained by the sympathetic nervous system. There have been no data present demonstrating that this condition can be treated with electroacupuncture and Chinese herbal medicine effectively. OBJECTIVE The objective of this study was to present ...