In herbal medicinal products the entire herbal drug or an herbal drug preparation is regarded as the active pharmaceutical ingredient, regardless of whether constituents with defined therapeutic activity are known. In quality control and stability testing of herbal medicinal products, fingerprint chromatograms are used as powerful tools to evaluate and compare the composition of compounds in su...

Due to the growing use of herbals and other dietary supplements healthcare providers and consumers need to know whether problems might arise from using these preparations in combination with conventional drugs. However, the evidence of interactions between natural products and drugs is based on known or suspected pharmacologic activity, data derived from in vitro or animal studies, or isolated ...

English herbals and floras', in which The Grete Herball of 1526, the second printed herbal in English, is subjected to "systematic analysis". Ryden's book is a philological study of The Grete Herbalrs 500 English plant names, their frequency of use, provenance, typology, and synonymy (i.e., identity). The purpose of the larger study of which this book is a part is to understand "continuity and ...

The irritable bowel syndrome (IBS) is a functional bowel disorder characterized by abdominal pain and altered bowel movements. The diagnosis of IBS is established by the Rome III criteria. IBS afflicts 10% to 15% of the US population (30 million Americans) and is the most common digestive disorder seen in the primary care setting. Patients with IBS have an impaired quality of life and high rate...

BACKGROUND Hyperlipidemia is one of the important diseases in pregnancy that causes fetal abnormalities during pregnancy and after the birth. Unfortunately, the usual anti-fat drugs are associated with high morbidity in fetus and due to people's inclination towards taking herbs, it is required to identify side effects of medicinal herbs in pregnancy. The aim of this study was to present hypolip...

Abstract Who were illustrated herbals intended for, who the actual readers and how did they use these books? The case of Dutch herbal Den groten herbarius met al sijn figueren (“The great with all its figures”) sheds light on book producers’ strategies popularisation readers’ personalisation. Between 1514 1547, at least six folio editions appeared, connections to German English traditions. work...

Historical research may be able to contribute to the exploration of traditional knowledge about medicinal plants and promising attempts have been made investigating Byzantine texts, Early Modern herbals, and writings of Christian missionaries. In this pilot study it should be explored if publications, travel reports, diaries or correspondence of the botanical explorers of the 19th and early 20t...

The 3Ks (kava, kratom and khat) are herbals that can potentially induce liver injuries. On the one hand, growing controversial data have been reported about the hepatotoxicity of kratom, while, on the other hand, even though kava and khat hepatotoxicity has been investigated, the hepatotoxic effects are still not clear. Chronic recreational use of kratom has been associated with rare instances ...