In the title compound, C(12)H(13)NO(4)S, a systemic fungicide, the heterocycle adopts a lounge chair conformation and the dihedral angle between the ring planes is 25.8 (2)°. Inter-molecular C-H⋯O hydrogen bonds are noted in the crystal structure. Also observed is a short inter-action of a methyl-ene hydrogen atom with the π-electron system of a phenyl ring in an adjacent mol-ecule.

Given the importance of heterocycle indole derivatives, much effort has been directed toward the development of methods for functionalization of the indole nucleus at N1 and C3 sites. Moreover, the platinum-catalyzed allyation of nucleophiles was an established and efficient way, which has been applied to medicinal and organic chemistry. In our research, the platinum-catalyzed 2,3-disubstitued ...

This review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactions. The review is divided according to the main heterocycle types in order of increasing complexity, starting with heterocyclic systems containing ...

In the title compound, C18H16N4OS, the six-membered heterocycle of the benzo-thia-zine fragment exhibits a screw-boat conformation. The dihedral angles between the plane through the triazole ring and those through the fused and terminal benzene rings are 76.68 (11) and 71.0 (1)°, respectively; the benzene rings are nearly perpendicular [dihedral angle = 79.6 (1)°]. In the crystal, mol-ecules ar...

In the title compound, C12H10Cl2N2O2, the seven-membered heterocycle displays a half-chair conformation. The mean plane through the oxo-propyl-idene group makes a dihedral angle of 36.44 (9)° with the fused benzene ring. An intra-molecular N-H⋯O hydrogen bond to close an S(6) loop is noted. An important feature of the mol-ecular packing are N-H⋯O hydrogen bonds that lead to the formation of hel...

The centrosymmetric title compound, [Cu(2)(C(10)H(8)N(2))(2)(C(25)H(22)P(2))(2)](BF(4))(2), consists of discrete dinuclear cations and tetra-fluoro-borate anions. The two Cu(I) centers are bridged by the phosphine ligands to form an eight-membered ring. The Cu(I) center exhibits a tetra-hedral coordination as it is chelated by the N-heterocycle.

The asymmetric unit of the crystal structure of the title compound, [Sn(C(7)H(6)Cl)(2)Cl(2)(C(20)H(14)N(4))], contains two independent mol-ecules. Each Sn(IV) atom is chelated by the bipyridine-like N-heterocycle and exists in a distorted trans-C(2)SnCl(2)N(2) octa-hedral coordination environment. One chloro-benzyl substituent is disordered in each mol-ecule in 0.5:0.5 and 0.778 (2):0.222 (2) r...

Though less potent than the parent natural product leinamycin, S-deoxyleinamycin displays activity against human cancer cell lines that is comparable to many clinically used agents. The results reported here suggest that the 1,2-dithiolan-3-one heterocycle found in S-deoxyleinamycin reacts with thiols to generate a persulfide intermediate (RSS(-)) that could deliver biologically active polysulf...

The reaction of tetrakis[bis(trimethylsilyl)methyl]digallane(4), 1, with 1,1′-ferrocenedicarboxylic acid afforded orange-red crystals of the macrocyclic compound 2 in a yield of 84%. 2 contains a large 32-atom heterocycle, which comprises four Ga-Ga single bonds bridged by four 1,1′-ferrocenedicarboxylato ligands. The largest diameter of the molecule is about 2.5 nm. The redox-active Ga-Ga site...

The Zn(II) atom in the title compound, [Zn(C(8)H(7)N(3)O(2)S)(C(10)H(8)N(2))], is N,N'-chelated by the heterocycle and N,O,S-chelated by the doubly deprotonated Schiff base ligand in a distorted square-pyramidal environment. O-H⋯O and N-H⋯N hydrogen bonds link adjacent mol-ecules into a layer structure.