In this work, Aliquat 336 ([Aliquat+]) based ionic liquids containing the fluorinated anion bis(trifluoromethylsulfonyl)imide [NTf2−] was successfully prepared by anionic exchange replacement of chloride anion. The reaction lithium with N-Methyl-N,N,N-trioctylammonium ([N1,8,8,8][Cl] in water lead to corresponding IL, namely ([Aliquat+][NTf2−]). obtained liquid characterized using infrared and ...

Three novel chelators based on the 6-amino-6-methylperhydro-1,4-diazepine scaffold and possessing three pendant N-acetic or N-α-methylacetic acid have been synthesised. The ligands contain six donor atoms for complexation of Mn(II) ions and thus potentially leave an additional site for coordination of a water molecule. The protonation constants of the ligands and the stability constants of thei...

The present investigation describes the synthesis and structural study of a metal-zinc ligand [NiL].H2O, which was used to generate trinuclear complex formulated as {Ni(m-L)Na(m-L)Ni}.(SCN)0.6.(Cl)0.4. title compound crystallizes in tetragonal space group I41/acd with following unit cell parameters: = 185403(5) Å, c 51.925(2) V 17849.0(3) Å3, Z 16, R1 0.074 wR2 0.209. Each organic molecule acts...

Mitochondria are the principal destination for labile iron, making these organelles particularly susceptible to oxidative damage on exposure to ultraviolet A (UVA, 320-400 nm), the oxidizing component of sunlight. The labile iron-mediated oxidative damage caused by UVA to mitochondria leads to necrotic cell death via adenosine triphosphate depletion. Therefore, targeted removal of mitochondrial...

Current iron chelation therapy consists primarily of DFO (desferrioxamine), which has to be administered via intravenous infusion, together with deferiprone and deferasirox, which are orally-active chelators. These chelators, although effective at decreasing the iron load, are associated with a number of side effects. Grady suggested that the combined administration of a smaller bidentate chela...

There is a growing interest in the development of new medical diagnostic tools with higher sensibility and less damage for the patient body, namely on imaging reporters for the management of diseases and optimization of treatment strategies. This article examines the properties of a new class of lanthanide complexes with a tripodal tris-3-hydroxy-4-pyridinone (tris-3,4-HOPO) ligand - NTP(PrHP)(...