Using density-functional theory-based molecular-dynamics simulations, we have investigated the equation of state for silicon in a wide range of plasma density and temperature conditions of ρ=0.001-500g/cm^{3} and T=2000-10^{8}K. With these calculations, we have established a first-principles equation-of-state (FPEOS) table of silicon for high-energy-density (HED) plasma simulations. When compar...

BACKGROUND Hypohidrotic ectodermal dysplasia (HED) is a severe developmental disorder in which nonallelic genetic heterogeneity has been demonstrated. Even though X-linked and autosomal recessive forms are phenotypically similar, identification of the way of transmission is mandatory to give reliable genetic counseling to the family and to address molecular studies. Complete examination of rela...

Background. State-level 'age 21' drinking laws conform generally with the United States National Minimum Drinking Age Act of 1984 (US), and are thought to protect young people from adverse drinking experiences such as heavy episodic drinking (HED, sometimes called 'binge drinking'). We shed light on this hypothesis while estimating the age-specific risk of transitioning from 1st full drink to 1...

LCLS Matter in Extreme Conditions (MEC) Instrument is an X-ray instrument that will be able to create and diagnose High Energy Density (HED) matter. The MEC laser system can generate hard X-ray due to the interaction of the laser and the plasma. This paper summarizes results of the shielding calculations performed to evaluate the radiation hazards induced by this hard X-ray source with Monte Ca...

A novel monoenergetic proton backlighter source and matched imaging detector have been utilized on the OMEGA laser system to study electric E and magnetic B fields generated by laser-plasma interactions and will be utilized in the future to radiograph implosions and high-energy density HED plasmas. The backlighter consists of an imploding glass microballoon with D He fuel, producing 14.7 MeV D ...

LLE Review, Volume 152 209 Under the facility governance plan implemented in FY08 to formalize the scheduling of the Omega Laser Facility as a National Nuclear Security Administration (NNSA) User Facility, Omega Facility shots are allocated by campaign. The majority (68.1%) of the FY17 target shots were allocated to the Inertial Confinement Fusion (ICF) Campaign conducted by integrated teams fr...

Maternal intake of dietary methyl-micronutrients (e.g. folate, choline, betaine and vitamin B-12) during pregnancy is essential for normal maternal and fetal methionine metabolism, and is critical for important metabolic processes including those involved in developmental programming. Maternal obesity and nutrient excess during pregnancy influence developmental programming potentially predispos...

The Rayleigh-Taylor (RT) instability affects a vast range of High Energy Density (HED) length scales, spanning from supernova explosions (10$^{13}$ m) to inertial confinement fusion (10$^{-6}$ m). In fusion, the RT is known induce mixing or turbulent transition, which in turn cools hot spot and hinders ignition. fine-scale features instability, are difficult image HED physics, may help determin...

Although mutations in cardiac sodium and potassium channel genes are associated with congenital long QT syndrome (LQTS), a "modifier" role of the sympathetic nervous system was proposed to explain the distinct severity of the disease. We evaluated cardiac sympathetic innervation using [11C]hydroxyephedrine ([11C]HED) and positron emission tomography (PET) in genotyped LQTS patients. H215O and [...

High Energy Density (HED) experiments at the HHT experimental site of the GSI Plasma Physics Group employ intense, energetic uranium beams in order to study new regimes of the equation of state (EOS) of matter under extreme conditions. A key parameter to be determined in these experiments is the density distribution in the irradiated and heated target. Determining the spatial and density distri...