ii Acknowledgements iii Table of

Cavitation often occurs in therapeutic applications of medical ultrasound such as shock-wave lithotripsy (SWL) and high-intensity focused ultrasound (HIFU). Because cavitation bubbles can affect an intended treatment, it is important to understand the dynamics of bubbles in this context. The relevant context includes very high acoustic pressures and frequencies as well as elevated temperatures....

Background Mild hyperthermia (41.5-44°C) has been shown to enhance the effect of radiotherapy and chemotherapy. However, currently available heating methods are often inefficient in inducing conformal hyperthermia for deep seated targets. Here, the software of Philips Sonalleve V2 MR-HIFU system was modified to enable performing a long duration large volume hyperthermia sonication in in-vivo po...

High-intensity focused ultrasound (HIFU) competes with radiofrequency and cryotherapy for the treatment of small renal masses as a third option among ablative approaches. As an emerging technique, its possible percutaneous or laparoscopic application, low discomfort to the patient and the absence of complications make this technology attractive for the management of small renal masses. This man...

The main method of treatment of breast fibroadenomas, until recently, was considered a surgical. However, there is research the authors of a new non-invasive method of treatment HIFU. The paper describes the mechanism of action and clinical features of the effect of treatment of fibroadenomas of the mammary glands by HIFU. Morрhocytology effects confirmation of the method HIFU ablation breast f...

Current HIFU challenges include amount of tissue that can be destroyed by a single exposure, the inability to treat through bone, difficulty in monitoring therapy in real‐time, and difficulty in planning the strategy before therapy. Technological advances such as multi‐transducer or array beam generator, instrumentation and image‐based guidance of HIFU treatment promise to overcome many of thes...

BACKGROUND To assess the long term efficacy and tolerability of one or two ultrasound (US)-guided high-intensity focused ultrasound (HIFU) treatment in patients with breast fibroadenoma (FA). METHODS Twenty patients with 26 FA were selected for US-guided HIFU. The therapy was performed in one or two sessions. FA volume was assessed before and followed up to 24 months after the last HIFU. Afte...

Background/introduction Magnetic resonance imaging (MRI) provides a wide spectrum of imaging contrasts, which have utility for preparation and evaluation of HIFU treatments, as well as for guiding HIFU energy delivery (MRgHIFU). Currently, research into the prospective value of these imaging markers and their ability to predict and probe treatment success is challenged by the lack of an analysi...

In the high-intensity focused ultrasound (US), or HIFU, field, it is well-known that the cavitation effect can be used to induce lesions of larger volume. The principle is based on the increase in the equivalent attenuation coefficient of the tissue in the presence of the bubbles created by cavitation. The elementary lesions produced by combination of cavitation and thermal effects, using focus...