PURPOSE Respiratory motion makes hepatic ablation using high intensity focused ultrasound (HIFO) challenging. Previous HIFU liver treatment had required apnea induced during general anesthesia. We describe and test a system that allows treatment of the liver in the presence of breathing motion. METHODS Mapping a signal from an external respiratory bellow to treatment locations within the live...

A shaped-based ultrasound tomography method is proposed to reconstruct ellipsoidal objects using a linearized scattering model. The method is motivated by the desire to detect the presence of lesions created by high intensity focused ultrasound (HIFU) in applications of cancer therapy. The computational size and limited view nature of the relevant three-dimensional inverse problem renders impra...

introduction: the medical applications of ultrasound on human brain are highly limited by the phase and amplitude aberrations induced by the heterogeneities of the skull. however, it has been shown that time reversing coupled with amplitude compensation can overcome these aberrations. in this work, a model for 2d simulation of the time reversal mirror technique is proposed to study the possibil...

Background/introduction Breast fibroadenomata (FAD) are the most common breast lesions in woman. For palpable lesions, three options are available: reassurance (with or without follow-up), vacuum assisted mammotome (VAM) or surgical excision. High intensity focused ultrasound (HIFU) is a non-invasive ablative technique in which an ultrasound (US) beam propagates through tissue as a high-frequen...

Background/introduction Fibroadenomas are common, benign lesions of the breast. A minority of fibroadenomas will disappear without treatment, but most increase in size or remain unchanged. Current management of patients with fibroadenomas in the United States varies on a case by case basis and includes observation or surgical excision. Many patients find their fibroadenoma bothersome, and opt f...

Tissue destruction by thermal ablation occurs when the targeted delivery of heat or cold causes a rapid change in temperature (>55°C for heat or <−20–50°C for cold) in the local tissue environment. Imaging can be used to localize and target the thermal effects to the target/tumor for treatment, control the energy deposition, and assess treatment response. Therapeutic applications of ultrasound ...

Efficient driving of piezoelectric materials is desirable when operating transducers for biomedical applications such as high intensity focused ultrasound (HIFU) or ultrasound imaging. More efficient operation reduces the electric power required to produce the desired bioeffect or contrast. Our preliminary work [Cole et al. Journal of Physics: Condensed Matter. 2014;26(13):135901.] suggested th...

The aim of this study was to determine the feasibility and safety of high intensity focused ultrasound's (HIFU) in pancreatic diseases. Twelve pigs were divided into three groups. The pancreases of pigs in Group A were ablated directly with HIFU, but those in Group B and C ablated by extracorporeal HIFU. The pigs in Group C were sacrificed at day 7 after HIFU. Serological parameters were determ...

PURPOSE To evaluate the clinical value of the contrast agent SonoVue in the treatment of uterine fibroids with ultrasound-guided high intensity focused ultrasound (HIFU) therapeutic ablation. MATERIALS AND METHODS A total of 291 patients with solitary uterine fibroid from three centers were treated with ultrasound-guided HIFU. Among them, 129 patients from Suining Central Hospital of Sichuan ...

High Intensity Focused Ultrasound (HIFU) allows non invasive treatment of uterine fibroids without anaesthesia and a fast return to normal activity [1]. For this thermotherapy procedure, MR guidance provides anatomical images to plan treatment of the fibroid, thermal maps to quantify the HIFU heating and contrast enhanced images to measure the induced nonperfused volume. This routine clinical p...