A systematic study was performed on the influence of charge and steric hindrance on the assembly into fibres of a series of pentameric peptides based on the well-known β-sheet forming sequence Gly-Ala-Gly-Ala-Gly, which were N-terminally acylated with pentacosadiynoic acid. To investigate the effect of steric hindrance and charge repulsion on the fibre structure, either the N-terminal or the C-...

Tile-based self-assembly systems are capable of universal computation and algorithmically directed growth. Systems such behaviors typically make use “glue cooperation” in which the glues on at least 2 sides a tile must match bind to those exposed perimeter an assembly for that attach. However, several models have been developed utilize “weak cooperation”, where only single glue needs but other ...