PURPOSE To describe a case of severe corneal granular dystrophy with clinicopathologic and molecular genetic findings. METHODS The DNAs of a 53-year-old male patient suffering from corneal granular dystrophy and nonaffected family members were analyzed by molecular genetic methods. Clinical features, and histopathologic and immunohistochemical findings from the penetrating keratoplasty specim...

OBJECTIVE To estimate the predictable value of histopathologic parameters in chronic rhinosinusitis (CRS) for response to endoscopic sinus surgery (ESS). STUDY DESIGN Symptomatology was rated in 100 patients prior to as well as 12 and 24 months after surgery. Specimens taken during the procedure were examined and scored for goblet cells, subepithelial thickening, mast cells, and eosinophils. ...

purpose: to characterize the histopathologic, electron microscopic and confocal scan features of ahram mineral water (amw)-induced keratopathy in cadaver corneas. methods: seven cadaver globes were examined, five of which were exposed to amw from the corneal side for different durations (30 seconds, 3, 15, 30, and 60 minutes) and the other two were considered as controls. after performing confo...

OBJECTIVE To determine histopathologic findings related to the indeterminate or inadequate result of fine-needle aspiration biopsy (FNAB) in papillary thyroid carcinomas (PTCs) and to correlate histopathological findings with ultrasonographic features of tumors. MATERIALS AND METHODS We retrospectively reviewed the medical records of FNAB, histopathologic characteristics, and sonographic find...

Establishing a definitive diagnosis for any form of alopecia can be challenging. Adding to the diagnostic complexity is the fact that many patients have more than one form of alopecia contributing to their hair loss. We conducted a review of 1360 consecutive scalp biopsy specimens submitted for the evaluation of scalp hair loss over a 16-month period, demonstrating that 12.5% of cases had a com...

building which the Admiralty acknowledged: "Though science is much respected by their Lordships and your paper is much esteemed, it is too learned." Young was also appointed as Superintendent of the Nautical Almanac and Secretary of the Board of Longitude. In this he was unable to satisfy the demands both of the navigators and of the astronomers, incurring the displeasure of both. A bibliograph...

OBJECTIVE To delineate the light and electron microscopic features of tissue removed at the time of macular hole surgery. METHODS The ocular fluid specimens were concentrated using Millipore filters and stained with a modified Papanicolaou and the periodic acid-Schiff stains in 697 cases. In 92 cases, surgically isolated tissue was processed and examined by electron microscopy. RESULTS The ...

The need for routine histopathological examination of gallbladders after cholecystectomy is debated. This study suggests that selective the gallbladder may be considered oncologically safe. While necessity a histopathologic as