We investigated the postnatal development of the thyrotropin-releasing hormone (TRH)-containing raphe system in the brainstem of neonatal rats. Postnatal changes in TRH expression in nucleus (n.) raphe obscurus (ROb) and n. raphe pallidus (RPa) were evaluated by in situ hybridization using an 35S-labeled oligonucleotide probe complementary to TRH precursor mRNA. TRH mRNA expression was low at b...

Harris (2006) recently proposed a new elemental model of the processes involved in associative learning. Although Harris explicated all relevant mathematical and conceptual details of the model in his article, implementing a computer simulation of his model requires considerable programming expertise and work. We therefore present the Harris model simulator (HMS), a MATLAB simulator of Harris's...

The paper discusses the complex, agent-oriented hierarchic memetic strategy (HMS) dedicated to solving inverse parametric problems. The strategy goes beyond the idea of two-phase global optimization algorithms. The global search performed by a tree of dependent demes is dynamically alternated with local, steepest descent searches. The strategy offers exceptionally low computational costs, mainl...

Heat-killed Pseudomonas aeruginosa are phagocytized much more slowly by human polymorphonuclear leukocytes than are the live organisms. The post-phagocytic increase in hexose monophosphate shunt activity (HMS) parallels the ingestion of the bacteria. The addition of serum to the live organisms causes a marked increase in both ingestion and cellular HMS activity; serum actually causes an inhibit...

We provide an overview of recent developments to the Hybrid Monte Carlo Simulation (HMS) model for calculating preequilibrium reactions. Illustrative examples are shown for nucleon and cluster induced reactions, and for assessing the importance of multiple preequilibrium processes. We present new results using HMS theory to study heavy nuclide recoil velocities, which are important in applicati...

−Three kinds of biochars (called poplar branch biochar (PBC), water hyacinth biochar (WHC), and corn straw biochar (CSC)) were prepared in a fixed-bed pyrolyzer at different pyrolysis temperature of 300-700 C. The effects of biochar species, pyrolysis temperature and biochar addition on adsorption characteristics of typical heavy metals (HMs) of Pb and Zn in vegetable soil (collected from lead-...

This paper deals with a real-time scheduling system of holonic manufacturing systems (HMSs), which were proposed by an international cooperative research consortium called The HMS Consortium for Autonomous Distributed Management and Control of the Manufacturing Systems. The scheduling system generates real-time suitable production schedules, based on decision making by individual constituents n...

The co-condensation of a tetraethoxysilane molecule on a neutral n-octylamine surfactant template is a convenient synthetic methodology for mesostructured material preparations. Distinct routes of template removal were investigated. The neutral surfactant was removed by calcination, hot solvent extraction, heating at 150 uC, in vacuo at room temperature and at 100 uC, and air drying, with the p...

The aim of the Health and Memory Study (HMS) of Nord-Trøndelag, Norway, was primarily to establish a database suitable as basis for a large number of studies on dementia. Data from the HMS study were collected via questionnaires and examinations during the period from 1995 to 2011. The dementia panel consists of 620 participants residing in nursing homes and 920 participants referred to memory ...

Middle East respiratory syndrome coronavirus (MERS-CoV) is continuously spreading and causing severe and fatal acute respiratory disease in humans. Prophylactic and therapeutic strategies are therefore urgently needed to control MERS-CoV infection. Here, we generated a humanized monoclonal antibody (mAb), designated hMS-1, which targeted the MERS-CoV receptor-binding domain (RBD) with high affi...