Rituximab (Rituxan) is a genetically engineered chimeric murine/human monoclonal antibody and the first monoclonal antibody to become available to physicians for the treatment of malignant disease. It has recently been licensed for use in the treatment of patients with relapsed or refractory low-grade or follicular, CD20 positive B-cell Non-Hodgkins Lymphoma (NHL). Its mechanism of action is by...

introduction: autologous stem cells have greatly influenced the treatment of a variety of malignancies including hodgkin/non-hodgkins lymphoma and acute leukemias. this is a preliminary study comparing the time of engraftment, mortality rate and cost of treatment in outpatient versus inpatient autologous stem cell transplantation (sct) in iran. patients and methods: 11 outpatients (6 hodgkin ly...

Type 2 diabetes is associated with increased risks for several cancers, including colon,1 postmenopausal breast,2 pancreatic,3 liver,4 endometrial,5 and bladder6 cancers and non-Hodgkins lymphoma.7 Type 2 diabetes is also linked to a modest decrease in the risk for prostate cancer.8 However, diabetes does not reduce aggressive forms, and prostate cancer mortality rates are higher among men with...

An aspect of the Anglo-New Zealand artist Frances Hodgkins (1869­­–1947) which has been largely overlooked by art historians is challenges that she faced with her eyesight, particularly from 1930s onwards. These are documented here, using letters to family and friends. The article then applies findings in pioneering studies ophthalmology Patrick Trevor-Roper John S. Werner a selection Hodgkins’...