BACKGROUND The aim of the study was to estimate the association between anthropometric obesity parameters, serum concentrations of ghrelin, resistin, leptin, adiponectin and homeostasis model assessment (HOMA-IR) in obese non-diabetic insulin-sensitive and insulin-resistant patients. MATERIAL/METHODS Study subjects included 37 obese (body mass index [BMI] ≥ 30 kg/m2) out-clinic patients aged ...

The anxiety, depression, and stress, along with diabetes, obesity, lack of vital power, many other threats to human health, are the issues which humans have face in 21st century due modern bad lifestyles. Many medicines scientific experiments find solution new ways through pharma industries being sought. present manuscript not only deals aspects on these all afore said issues, but also scientif...

AIM The aim of this study is to investigate the relationship between the common C49620T polymorphism in the sulfonylurea receptor (SUR1) gene and glucose metabolism, β-cell secretory function and insulin resistance in women with a history of gestational diabetes (GDM). MATERIAL AND METHODS Study group included 199 women, diagnosed GDM within the last 5-12 years and control group of comparable...

Aims This study investigated the relationship between waist circumference and the subsequent incidence of type 2 diabetes and the association with insulin resistance and beta-cell function in relatively lean Japanese. Methods The study participants were 3,992 employees (2,533 men and 1,459 women, 35-55 years old) of a metal-products factory in Japan. The incidence of diabetes was surveyed in an...

BACKGROUND/AIMS Insulin resistance (IR) plays an important role in the pathogenesis of diabetes and non-alcoholic fatty liver disease (NAFLD). Current methods for insulin resistance detection are cumbersome, or not sensitive enough for early detection and follow-up. The BreathID system can continuously analyse breath samples in real-time at the point-of-care. Here we determined the efficacy of ...

BACKGROUND Ferritin is known to be associated with insulin resistance (IR) and oxidative stress; however, recent studies have shown that there is an association between ferritin and anti-oxidative status. To date, the biphasic response of ferritin to oxidative stress has not been fully evaluated. Thus, we investigated the association between ferritin and IR and anti-oxidative status in obese an...

The purpose of this study is to look at these relationships in non-diabetic Korean adults. This study was based on data from the KNHANES V-1, which is representative of the population of Korea. A total of 5,492 participants (≥20 years in age) without type 1 or type 2 diabetes, assessed for serum 25-hydroxyvitamin D [25(OH)D], fasting blood glucose and insulin, as well as anthropometric variable...

The point-counterpoint articles in the September issue of Diabetes Care (1,2) raise several interesting issues on our understanding of insulin resistance, homeostasis model assessment (HOMA), and the future of measurement shortcuts for insulin resistance and secretion. McAuley et al. (1) provide an overview of methods to assess insulin sensitivity and secretion. The conditional nature of the ti...