Introduction A series of cell-line specific complex media supplements have been developed for enhancing performance of various biopharmaceutical production systems. Created using in-house media optimization methods, these supplements are manufactured using innovative, proprietary process technology which allows for the combination of complex and/or chemically defined animal-component free media...

We study the effect of mass media, modeled as an applied external field, on a social system based on Axelrod's model for the dissemination of culture. The numerical simulations show that the system undergoes a nonequilibrium phase transition between an ordered phase (homogeneous culture) specified by the mass media and a disordered (culturally fragmented) one. The critical boundary separating t...