OBJECTIVE Perivitelline fluid (PVF) of the horseshoe crab embryo has been reported to possess an important role during embryogenesis by promoting cell proliferation. This study aims to evaluate the effect of PVF on the proliferation, chromosome aberration (CA) and mutagenicity of the dental pulp stem cells (DPSCs). MATERIALS AND METHODS This is an in vitro experimental study. PVF samples were...

BACKGROUND Horseshoe crabs are marine arthropods with a fossil record extending back approximately 450 million years. They exhibit remarkable morphological stability over their long evolutionary history, retaining a number of ancestral arthropod traits, and are often cited as examples of "living fossils." As arthropods, they belong to the Ecdysozoa, an ancient super-phylum whose sequenced genom...

The horseshoe crab Limulus polyphemus (Linnaeus, 1758) is a famous species, renowned as ‘living fossil’ (Owen, 1873; Barthel, 1974; Kin and Błażejowski, 2014) for its apparently little-changed morphology many millions of years. genus Müller, 1785 was used by Leach (1819, p. 536) the basis new family Limulidae synonymized it with Polyphemus Lamarck, 1801 (Lamarck's proposed but later unaccepted ...