A sensitive (0.01-1 nmol) method has been developed for the analysis of polyamines in higher plant extracts based on high performance liquid chromatography (HPLC) of their benzoyl derivatives (Redmond, Tseng 1979 J Chromatogr 170: 479-481). Putrescine, cadaverine, agmatine, spermidine, spermine, and the less common polyamines nor-spermidine and homospermidine can be completely resolved by rever...

The present study describes development and subsequent validation of high performance liquid chromatographic method (HPLC) in comparison with spectrophotometric methods (classic, first, second and third order derivative) for determination of pure cilazapril in substance and pharmaceutical preparation. The main aim of this study was to find the method suitable not only for determination of cilaz...

D-glucoside, Fig. 1) is a potent clinical anticancer agent. It is active against several tumors including small lung cancers, lymphoma, leukemia and Karposi’s sarcoma associated with AIDS. It is used as part of the preparatory regimen for bone marrow transplants in patients with advanced hematological malignancies. The mechanism of action of etoposide is unknown but it is a cell-cycle, phasespe...

Abstract Background Apigenin (4?, 5, 7-trihydroxyflavone), a flavonoid, is present usually in fruits and vegetables possessing numerous biological properties like antioxidant, anti-viral, antibacterial, anti-inflammatory, chemoprevention activity. So study was aimed to prepare characterize nanoliposomes of apigenin estimate its encapsulation efficiency by stability-assisted reverse-phase (RP)-H...

High-performance liquid chromatography (HPLC) technique for cyamemazine tartrate (CYMT) was developed and validated according to the International Conference on Harmonization (ICH) Q2 (R1) guidelines. The method estimating CYMT from a bulk its pharmaceutical dosage form found be simple, precise, accurate, fast, stable reverse phase HPLC (RP-HPLC) approach. For chromatographic separation, Hypers...