Linkage disequilibrium mapping is an important tool in disease gene mapping. Recently, Toivonen et al. [1] introduced a haplotype mining (HPM) method that is applicable to data consisting of unrelated high-risk and normal haplotypes. The HPM method orders haplotypes by their strength of association with trait values, and uses all haplotypes exceeding a given threshold of strength of association...

Hypermutable (HPM) strains of Pseudomonas aeruginosa have been found at high frequencies in cystic fibrosis (CF) patients in Europe. We report the results of testing for HPM frequencies, mutator genotype, and antimicrobial resistance of P. aeruginosa strains from Brazilian CF patients. A modified disk diffusion technique was used to quantify antibiotic-resistant subpopulations of an isolate, an...

In this paper, the homotopyperturbation method (HPM) is employed to obtain approximate analytical solution to the linear and nonlinear systems of partial differential equations (PDEs). HPM yields solutions in convergent series forms with easily computable terms. Generally, the closed form of the exact solution or its expansion is obtained without any noise terms. Test examples demonstrate the e...

Based on the homotopy perturbation method (HPM) and Padé approximants (PA), approximate and exact solutions are obtained for cubic Boussinesq and modified Boussinesq equations. The obtained solutions contain solitary waves, rational solutions. HPM is used for analytic treatment to those equations and PA for increasing the convergence region of the HPM analytical solution. The results reveal tha...

Aim of the paper is to investigate applications of Homotopy Perturbation Method(HPM) on non-linear physical problems .Some coupled non-linear partial differential equations are considered and solved numerically using Homotopy Perturbation Method. The results obtained by HPM are compared with those obtained by Adomian Decomposition Method. The behavior of Homotopic solution is shown through grap...

In this Letter, we apply the homotopy-perturbation method (HPM) to obtain approximate analytical solutions of the time-dependent Emden– Fowler type equations. We also present a reliable new algorithm based on HPM to overcome the difficulty of the singular point at x = 0. The analysis is accompanied by some linear and nonlinear time-dependent singular initial value problems. The results prove th...

OBJECTIVE To evaluate the influence of high-pitch mode (HPM) in dual-source computed tomography (DSCT) on the accuracy of three-dimensional (3D) volumetry for solid pulmonary nodules. MATERIALS AND METHODS A lung phantom implanted with 45 solid pulmonary nodules (n = 15 for each of 4-mm, 6-mm, and 8-mm in diameter) was scanned twice, first in conventional pitch mode (CPM) and then in HPM usin...

Major areas considered under the rubric of health and productivity management (HPM) in American business include absenteeism, employee turnover, and the use of medical, disability, and workers' compensation programs. Until recently, few normative data existed for most HPM areas. To meet the need for normative information in HPM, a series of Consortium Benchmarking Studies were conducted. In the...

BACKGROUND Outpatient palliative care, an evolving delivery model, seeks to improve continuity of care across settings and to increase access to services in hospice and palliative medicine (HPM). It can provide a critical bridge between inpatient palliative care and hospice, filling the gap in community-based supportive care for patients with advanced life-limiting illness. Low capacities for d...

We have previously documented the regional distribution of 70-kDa heat shock protein (HSP70) in brains of rats made hyperthermic by brief exposure to high-powered microwaves (HPM; 2.06 GHz). We now compare HSP70 expression induced by HPM exposure to that induced by exertional and/or environmental heat stress. Rats were chronically implanted with a temperature probe guide in the hypothalamic reg...