background: fanconi anemia (fa) is an autosomal recessive disorder characterized by congenital malformations, bone marrow failure, development of squamous cell carcinoma (scc), and other cancers. human papillomavirus (hpv) in the oral cavity or oropharynx has been associated with an increased risk of laryngeal papillomatosis, invasive squamous cell carcinoma of the head and neck (hnscc) and cer...

abstract background: cancers are the second most common cause of non-accidental deaths in iran, after cardiovascular mortality. although most cases of esophageal squamous cell carcinoma (escc) in the usa and western populations have been attributed to high levels of exposure to tobacco and alcohol, but in iranian populations the other risk factors especially infectious agents have been postulat...

Aim: Head and Neck Squamous Cell Carcinoma (HNSCC) is a global health problem whose incidence varies by geographic region race according to risk factors. Human papillomavirus (HPV) infection significant factor for HNSCC. HPV-16 HPV-18 are two forms of HPV that carcinogenic. HNSCCs positive have better prognosis rather than negative. The purpose this research was characterize HPV-16, -18 variati...

background: carcinomas of esophagus, mostly squamous cell carcinomas, occur throughout the world. there are a number of suspected genetic or environmental etiologies. human papilloma virus (hpv) is said to be a major etiology in areas with high incidence of esophageal carcinoma, while it is hardly detectable in low incidence regions. this study was designed to evaluate the prevalence of hpv in ...

background: prostatic adenocarcinoma is the most prevalent cancer and the second cause of cancer-related death among men. human papilloma virus (hpv) considered as a preventable risk factor for prostatic adenocarcinoma. in this study, we detected the frequency of hpv infection in prostatic adenocarcinoma and benign prostatic hyperplasia (bph) in isfahan. materials and methods: in this study, 12...

Persistent high-risk (HR) human papillomavirus (HPV) infection is an essential risk factor for cervical carcinoma and precancerous lesion. There are differences in HPV distribution among different countries, regions ethnic groups. The aim of this research was to reveal the epidemiological characteristics Chongqing, China. In study, 13,788 women aged 18 78 were screened 23 genotypes by PCR-rever...

hpv vaccine has been recently added to the iran drug list, so decision makers need information beyond that available from rcts to recommend funding for this vaccination. modeling and economic studies have addressed some of those information needs. we reviewed cost effectiveness studies to find a suitable model for iranian population to determine the potential cost effectiveness of hpv vaccine p...

background and objectives: breast cancer is the most common malignancy in women throughout the world. there are controversial reports on the role of human papillomavirus (hpv) infection in breast carcinogenesis. the aim of this study was to assess the presence of hpv-dna in invasive breast carcinoma to determine the association between hpv infection and breast carcinoma. methods: the study incl...

objective(s): valproic acid (vpa) has proven to be as one of the most promising useful drug with anticancer properties.in this study, we investigate the vpa effects on e-cadherin expression in hela, tc1, mkn45, and hct116 cell lines.  this study assesses the effects of vpa on human papillomavirus e7 expression in hpv positive cell lines. materials and methods: cell lines were treated by2 mmol/l...

introduction: certain types of human papillomavrus (hpv) are associated with cervical intraepithelial neoplasia (cin) and squamous cell carcinoma (scc). the aim of theobservations reported here was to determine whether the prognosis for invasive cancers of the uterine cervix is related to the type of human papillomavirus asociated with the tumor. material and methods: twenty patients with invas...