the previous studies reported some information about prevalence release of high-risk hpv types in hsil or cervical cancer globally and in iran, however, this information is not enough for final judgment about vaccination against hpv or any screening program. the aim of the present study was to assess the hpv type distribution in hsil and icc specimens of women attending shahid beheshti universi...

Oropharyngeal squamous cell carcinoma (OPSCC) has historically been attributable to tobacco and alcohol exposure saw a decline in incidence after societal norms shifted away from smoking. In recent decades, this disease had re-emergence due human papillomavirus (HPV) infection, now surpassing cervical cancer as the number 1 cause of HPV-related United States. HPV-positive OPSCC differs HPV-nega...

Background: Gastrointestinal (GI) malignancies are the most common cancers and account for nearly half of all cancer-related deaths in Iran. There was a strong association between human papillomavirus (HPV) infection and urogenital cancers, in particular the cervix. However, there is no clear causal relationship in all types of cancers, including gastrointestinal cancers. Therefore, the present...

the purpose of the present study was to estimate the frequency of hpv dna in four groups of oral lesions, including oral squamous cell carcinoma. sixty paraffin-embedded oral tissue samples were examined for the presence of hpv dnas using the pcr technique. these specimens were obtained from patients with oral squamous cell carcinoma (oscc), leukoplakia, oral lichen planus (olp), and pyogenic g...

Abstract Background and Aims: Cervical cancer is among leading causes of cancer related death in women and human papilloma virus (HPV) is one of the important risk factor of this cancer. The aim of the present study was to develop a PCR method for identification of a high carcinogenic type of HPV, HPV 18 using E6 gene as a marker in patients with cervical cancer Materials and Methods: 9...

Objective(s): In the current work, poly D, L lactide-co-glycolide (PLGA) particles were applied for a viral vaccine for the delivery of antigens in cytosolic pathway by increasing the antigen presentation to T-lymphocytes. HPV-E7 protein with PLGA particles has been reported as a potent adjuvant for HPV vaccine by encapsulating protein into the PLGA particles. Polysaccharide from Pleurotus sajo...

Abstract Head and neck squamous cell carcinoma (HNSCC) is amongst the rapidly growing form of cancer associated with high mutation burden Human Papilloma virus (HPV) infection presenting approximately 800,000 new cases 400,000 deaths annually. HPV-positive HNSCC has been strongly better prognosis than HPV-negative due to immune activation in tumor microenvironment including cytotoxic CD8+ T cel...

Background: Some respiratory diseases may induce alveolar hypoxia thereby hypoxic pulmonary vasoconstriction (HPV). However, the mechanisms of this physiologic phenomenon are not fully understood. This study was the first to investigate the role of anion exchanger in sustained HPV.Methods: Experiments were performed in the isolated perfused rabbit lung. After preparation, the lungs were divided...