BACKGROUND We developed an evidence service that draws inputs from Health Systems Evidence (HSE), which is a comprehensive database of research evidence about governance, financial and delivery arrangements within health systems and about implementation strategies relevant to health systems. Our goal was to evaluate whether, how and why a 'full-serve' evidence service increases the use of synth...

OBJECTIVE In view of the fact that height differences between socio-economic groups are apparent early in childhood, it is of interest to examine whether skeletal growth is reflective of the social class gradient in CVD risk. The present study examined blood pressure levels, adiposity and growth of adolescent boys from high and low social classes. DESIGN In a cross-sectional study, skeletal g...

UNLABELLED It is important that resources for orthodontic treatment within the Health Service Executive (HSE) are directed towards those children most in need of treatment. At present, children are referred using existing HSE guidelines. OBJECTIVES To assess the level of treatment need in a sample of patients on the orthodontic waiting list in the North Eastern division of the HSE using the I...

This report summarises the findings of a follow-up study to the HSE/DETR/Home Office/HM Treasury Project 'relativities' study (HSE CRR 273/2000), which sought to elicit public preferences for preventing fatalities in several hazard contexts (railway/road accidents and public/home fires). The very public debate in the media and elsewhere regarding the organisation of rail safety following the La...

Multiple heat shock transcription factors (HSFs) have been discovered in several higher eukaryotes, raising questions about their respective functions in the cellular stress response. Previously, we had demonstrated that the two mouse HSFs (mHSF1 and mHSF2) interacted differently with the HSP70 heat shock element (HSE). To further address the issues of cooperativity and the interaction of multi...

Monaurally deaf people lack the binaural acoustic difference cues in sound level and timing that are needed to encode sound location in the horizontal plane (azimuth). It has been proposed that these people therefore rely on spectral pinna cues of their normal ear to localize sounds. However, the acoustic head-shadow effect (HSE) might also serve as an azimuth cue, despite its ambiguity when ab...

Posttraumatic Stress Disorder (PTSD) is associated with maladaptive changes in self-identity, including impoverished perceived self-efficacy. This study examined if enhancing perceptions of self-efficacy in combat veterans with and without symptoms of PTSD promotes cognitive strategies associated with positive mental health outcomes. Prior to completing a future thinking and social problem-solv...

OBJECTIVE To characterize the numerical profile of patients with acquired brain disorders. METHOD We investigated numeracy skills in 76 participants--40 healthy controls and 36 patients with neurodegenerative disorders (Alzheimer dementia, frontotemporal dementia, semantic dementia, progressive aphasia) and with focal brain lesions affecting parietal, frontal, and temporal areas as in herpes ...

Estimation of permeation of compounds such as chemical warfare agents (CWAs) alone or through barrier creams such as SERPACWA (Skin Exposure Reduction Paste Against Chemical Warfare Agents) requires animal experiments or in vitro testing using animal or human skin. While animal skin does not reflect the same barrier properties as human skin, human skin poses problems of procurement, cost and la...

Within the UK exposure of the consumer to pesticides via food is under the jurisdiction of the Pesticide Safety Directorate (PSD). However, the UK Health and Safety Executive (HSE) also has an input into the pesticide approvals process and this is related to worker safety. In terms of agricultural use, HSE has always had a watching brief as far as operator exposure is concerned either by doing ...