Previous studies have demonstrated the presence of human T-lymphotropic virus type I (HTLV-I) andlor HTLV type I1 (HTLV-11) in certain populations in Data on qualified blood donors are limited primarily to those in the southeast region of Brazil, while the country's 8,400,000 square miles include diverse geographic, climatic, and sociodemographic characteristics. To assist in the formulation of...

introduction: human t cell lymphotropic l.irus type i is responsible for adult t cell leukemia/lymphoma and htlv-i associated myelopathy. the aim of this study was constructing two reporter plasmids to enable us to evaluate the effects of htlv-i tax protein upon intra cellular signalling pathways which recruit creb and nfkb proteins. material and methods: a complete coding region of bacterial b...

Abstract Backgrounds Therefore, reports on the risk of HTLV-1-related diseases in organ transplantation have increased recent years, and management HTLV renal remains a challenge. Patients methods We retrospectively analyzed four HTLV-1-positive recipients or donors among 89 cases from 2006 to 2021. Results Among recipients, two patients developed adult T cell leukemia/lymphoma (ATL) derived at...

OBJECTIVE(S) Human T Lymphocyte Virus Type one (HTLV-I) is a retrovirus that infects about 10-20 million people worldwide. Khorasan province in Iran is an endemic area. The majority of HTLV-I-infected individuals sustain healthy carriers but small proportion of infected population developed two progressive diseases: HAM/TSP and ATL. The proviral load could be a virological marker for disease mo...

Introduction Conclusions References

Apart from HIV two exogenous retroviruses (human T cell leukaemia viruses type I (HTLV-I) and type II (HTLV-II)) infect humans. HTLV-I infection is endemic in Japan, the Caribbean, Africa, and Melanesia and is found among immigrants from these regions in Europe. HTLV-I infection is associated with a 1-5% lifetime risk of adult T cell leukaemia/lymphoma, a 0.25% lifetime risk of HTLV-I associate...

About 1% of people infected with the human T-cell leukaemia virus, type 1 (HTLV-I) develop a disabling chronic inflammatory disease of the central nervous system known as HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Patients with HAM/TSP have a vigorous immune response to HTLV-I, and it has been widely suggested that this immune response, particularly the HTLV-I-specific...

Karyotypes of 26 human lymphocyte cultures, infected or noninfected with human T-lymphotropic virus type I (HTLV-I), with or without Epstein-Barr virus infection, were analyzed by G-banding. Hypodiploidy and structural abnormalities were seen more frequently in HTLV-I-infected cultures (30%) than in virus noninfected cultures (10%) propagated for less than 200 days. In all of six immortalized c...

Serologic screening for human T-cell leukemia virus type I (HTLV-I) infection was begun in US blood banks with the licensure of enzyme-linked immunosorbent assays (ELISA) in December 1988. We examined the donation histories of the first 60 Western blot (WB)-confirmed HTLV-I/II positive donors to one blood center and found 8 had made 16 previous donations that scored negative on the screening EL...