background: kaposi’s sarcoma is a vascular malignancy, which frequently occurs among immunocompromised individuals such as transplant recipients and patients with acquired immunodeficiency syndrome. human herpesvirus 8 (hhv-8) is considered the etiological agent of all forms of kaposi’s sarcoma. though some seroepidemiological studies conducted on the prevalence of hhv-8 in iran, there are insu...

objective(s): to investigate the expression of human papilloma virus (hpv) l1 capsid protein, and human telomerase rna component (hterc) in cervical cancer and the role of detection of both genes in screening of cervical cancer.   materials and methods: a total of 309 patients were recruited and cervical exfoliated cells were collected. immunocytochemistry was employed to detect hpv l1 capsid p...

conclusions our results demonstrated a novel h7n9 virus in chickens in taizhou city in 2013 that may pose a potential risk to public health. results of 150 samples tested, 7 were detected to be h7n9 positive which all were collected from chickens. also, a novel h7n9 virus strain (a/chicken/jiangsu/1021/2013) was isolated and studied. phylogenetic analysis showed the novel isolated h7n9 virus ha...

Background and Aims: The emergence of drug-resistant influenza viruses has become a serious threat for human and animal populations. Glycyrrhiza glabra (Gg) is a traditional medicine clinically used for the treatment of viral respiratory infection symptoms in most countries. We evaluated the effects of the herb on influenza virus replication in human lung cultured cells (A549) following the det...

background: the human t-cell lymphotropic virus type i is the first retrovirus idenfied in humans. the virus has been associated with adult t-cell leukemia/lymphoma, human t-lymphotropic virus type i, myelopathy/tropical spasc paraparesis, uveis, arthris, pulmonary lymphocyc alveolis, keratoconjuncvis sicca, and infecous dermas. human t-lymphotropic virus type iis endemic in japan, p...

introduction: the human papilloma virus (hpv) can play a role in the development of head and neck squamous cell carcinoma (scc). our aim was to assess the prevalence of hpv dna in scc of the larynx. the impact of hpv infection on patient survival was also evaluated.  materials and methods: this case-control study was performed in 44 patients with scc of the larynx (case group), while the contro...

conclusions the results of this meta-analysis showed that gardasil and cervarix vaccines are highly effective against cervical cancer. according to the point that approximately 50% of cervical cancers and human carcinogenicity are related to hpv-16 infection, the bivalent hpv vaccine might have protective effects against hpv-16 cin2-3 lesion and cervical cancer. results by combining the results...

objective: the aim of this study was to investigate the existence of human t-lymphotropic virus type 1 (htlv-1) in subgingival plaque of htlv-1 seropositive pa-tients. materials and methods: a total of 18 patients including 13 females and fivemales, with a mean age of 37 years participated in this descriptive study. half of them were htlv-1 carriers and the others were in htlv-1 associated myel...

introduction: during the past few years, an increasing body of evidence has suggested a possible role for human herpes virus 6 (hhv-6) in multiple sclerosis (ms) pathogenesis. despite the many reports supporting the relationship between hhv-6 and ms, this association has not been definitely proved or refuted, and the matter remains unresolved. the current study was aimed to investigate any rela...

introduction: inactivated influenza vaccines are traditionally produced in chicken embryonated eggs but its limitations in producing the required doses in pandemic outbreaks quickly enough has made searching for alternative modes of production necessary. the use of cell culture-based vaccine production is one way of overcoming the limitations of the egg-based method and securing a more rapid re...