BACKGROUND Hyperthermia is considered an efficient complement in the treatment of head and neck squamous cell carcinoma (HNSCC). Hyperthermia induces cell apoptosis in a temperature- and time-dependent manner. However, the molecular mechanism of hyperthermia remains unclear. The aim of this study was to investigate the mechanism of apoptosis induced by ultrasound hyperthermia in HNSCC cell line...

The role of hyperthermia during regional alkylating agent chemotherapy is controversial. The aim of this study was to determine the exact contribution of hyperthermia to tumor response during isolated limb infusion with l-phenylalanine mustard. Rats bearing rodent fibrosarcoma on the hindlimb underwent isolated limb infusion with saline, saline plus heat, l-phenylalanine mustard, l-phenylalanin...

OBJECTIVE To determine the frequency of hyperthermia in acute ischemic stroke patients visiting a tertiary care hospital in a developing country. STUDY DESIGN Cross-sectional, observational study. PLACE AND DURATION OF STUDY Medical Wards of Civil Hospital, Karachi, from January to June 2013. METHODOLOGY Patients aged ≥18 years of either gender with acute ischemic stroke presenting within...

Fatal hyperthermia as a result of 3,4-methylenedioxymethamphetamine (MDMA) use involves non-esterified free fatty acids (NEFA) and the activation of mitochondrial uncoupling proteins (UCP). NEFA gain access into skeletal muscle via specific transport proteins, including fatty acid translocase (FAT/CD36). FAT/CD36 expression is known to increase following chronic exercise. Previous studies have ...

In a V-2 model of solitary hepatic metastasis, residual tumor was histologically identified in the treatment field in only three of 14 (21%) animals subjected to microsphere embolization of tumor arterioles plus focal (43°C, 40 min) hyperthermia compared with seven of ten (70%) subjected to focal (43°C, 40 min) hyperthermia alone (/' < 0.05), five of seven (71%) (P < 0.05) treated by occlusio...

Cobalt ferrite nanoparticles (CoFe2O4) are well known for some distinctive characteristics such as high magnetic permeability and coercive force, good saturation magnetization, excellent physical, and chemical stability, which make them so attractive for magnetic storage, magnetic resonance imaging (MRI), drug delivery, optical-magnetic equipment, radar absorbing materials...

Letter to the Editor concerns the question of a discussion of awake porcine malignant hyperthermia that erroneously omits the awake human stress reaction of malignant hyperthermia.

The applications of mathematical simulations of tissue tem perature distributions in hyperthermia treatments are discussed in terms of four areas, comparative, prospective, concurrent, and retrospective thermal dosimetry. These four aspects of thermal dosimetry cover the range of hyperthermia applications of interest to clinicians, from comparative evaluation of compet itive heating modalities ...

background: the purpose of this study was to investigate the enhanced thermal resistance mechanism of the du145 tumor spheroid cultures as compared to the prostate carcinoma cell line's monolayer cultures. materials and methods: du145 cells were cultured either as spheroids or monolayers. cultures were treated with hyperthermia in a precision water bath (at 43°c for 60 minutes) and/or quercetin...