BACKGROUND Overt hyperthyroidism has been associated with cardiac arrhythmias, hypercoagulopathy, stroke, and pulmonary embolism, all of which may increase mortality. Some, but not all, studies show an increased mortality in patients with hyperthyroidism. This inconsistency may be due to differences in study design, characteristics of participants, or confounders. In order to test whether hyper...

BACKGROUND Several epidemiologic studies have shown a possible association between thyroid function and cognitive decline. Our aim was to evaluate the association of subclinical hyperthyroidism and dementia in a population sample of older people METHODS A cross-sectional study--São Paulo Ageing & Health Study (SPAH)--in a population sample of low-income elderly people > or = 65 years-old to e...

PURPOSE Ventricular repolarization is assessed using the QT interval corrected by the heart rate (QTc) via an electrocardiogram (ECG). Prolonged QTc is associated with an increased risk of arrhythmias and cardiac mortality. As there have been few reports regarding the effects of hyperthyroidism on ventricular repolarization, we studied the association between serum free thyroxine (free T4 [fT4]...

Context There are contradictory results on the effect of hyperthyroidism on hemostasis. Inadequate population-based studies limited their clinical implications, mainly on the risk of venous thromboembolism (VTE). The present review focuses on hemostatic changes in overt and subclinical hyperthyroidism. Methods A systematic literature search was conducted employing MEDLINE database. The follow...

We have read with great enthusiasm the recently published article entitled “Association of inflammation with atrial fibrillation (AF) in hyperthyroidism” by Ozaydin and coworkers. In that very well-designed study, Ozaydin and coworkers tried to evaluate the relationship between serum levels of high-sensitivity C-reactive protein (HsCRP), as a marker of inflammation and the development of AF in ...

INTRODUCTION AND AIM About 15% of hyperthyroid patients suffer from gastrointestinal symptoms such as diarrhea, constipation, nausea and early satiety the problem. Published reports on the topic of gastric emptying in hyperthyroidism are rare and discrepant in their results. PATIENTS AND METHODS Thirteen patients (8 women, 5 male; aged 41.92+/-1.491 SE yr) with a recently established diagnosi...

Hepatic dysfunction is commonly observed in subjects with hyperthyroidism. Hepassocin a hepatokine playing an important role metabolic diseases and exhibiting hepatic protective effect. Nevertheless, the relationship between hepassocin hyperthyroidism was still unknown. In present study, total of 36 Graves’ disease were enrolled, we found that alanine aminotransferase (ALT) levels significantly...

OBJECTIVE The association between thyroid disease and breast cancer risk remains unclear. We, therefore examined the association between hypothyroidism, hyperthyroidism and breast cancer risk. DESIGN This was a population-based cohort study. METHODS Using nationwide registries, we identified all women in Denmark with a first-time hospital diagnosis of hypothyroidism or hyperthyroidism, 1978...

OBJECTIVES This study sought to prospectively evaluate the prevalence of cardiovascular abnormalities in patients with overt hyperthyroidism before and after antithyroid therapy. BACKGROUND Overt hyperthyroidism is associated with recognized cardiovascular effects believed to be reversed by antithyroid therapy; however, increasing data suggest significant long-term cardiovascular mortality. ...

Cardiovascular complications during hyperthyroidism are dominated by arrhythmias, heart failure and coronary disease. Pericardial effusion which is a common complication of hypothyroidism extremely rare in hyperthyroidism. We report the case 45-year-old woman admitted for management pleuro-pericarditis associated with atrial fibrillation context cardiothyreosis. The treatment consisted pericard...