OBJECTIVES To determine the incidence of posttreatment hypothyroidism in patients treated with surgery with or without radiotherapy for advanced-stage nonthyroid head and neck cancer and to make recommendations for its detection. DESIGN A prospective study to assess the incidence and time frame of occurrence of hypothyroidism in patients by primary tumor site and treatment modality. Thyroid f...

OBJECTIVE To evaluate the frequency of non-autoimmune subclinical and overt hypothyroidism in children with idiopathic steroid-resistant nephrotic syndrome (SRNS). METHODS This cross-sectional study recruited 30 children (age 1-18 y) with idiopathic SRNS; and 30 healthy controls. Serum T3, T4 and TSH were performed in cases as well as controls. Anti-thyroid peroxidase and anti-thyroglobulin a...

The incidence of hypothyroidism in India is high and it is not adequately controlled. The pathogenesis of hypothyroidism is not very clear, however increased oxidative stress have been reported. Pathological consequences of hypothyroidism point to a high potential for antioxidant imbalance. The present study was carried out to evaluate oxidative stress (MDA, Vitamin C) and to correlate these pa...

BACKGROUND There is a paucity of data on knowledge, awareness, and practices (KAP) of patients with hypothyroidism in India. AIMS AND OBJECTIVES To study the KAP and adherence to treatment of participants with primary hypothyroidism. MATERIALS AND METHODS An observational cross-sectional study was conducted in Endocrinology Outpatient Department of Maharaja Agrasen Hospital, Punjabi Bagh, N...

Introduction: Hypothyroidism has long been known for its effects on different organ systems, leading to hypometabolism. However, subclinical hypothyroidism, its most prevalent form, has been recently related to cardiovascular risk and also to maternal-fetal complications in pregnant women. Objectives: In these clinical practice guidelines, several aspects of this field have been discussed with ...

BACKGROUND: Many patients using warfarin may be at risk of international normalized ratio fluctuations. This may cause severe massive gastrointestinal or cerebral bleeding. Subclinical hypothyroidism in our population is highly prevalent (range from 3.1% to 8.4% for males and females respectively). Overt hypothyroidism diminishes the effect of warfarin but there is a lack of results on the effe...

Introduction: Congenital hypothyroidism is the most common cause of mental retardation in the world. The presence of hypothyroidism in fetal is lead to abnormalities in major organs, including nervous system and central skeleton. Aim of this study was to investigate epidemiologic situation of neonatal hypothyroidism in Ilam province between 2005 -2011. Materials and methods: This was a cross-s...

BACKGROUND Few population-based studies report the changes with time in thyroid function tests in patients with subclinical hypothyroidism. We compared the risk for developing overt hypothyroidism in patients with subclinical hypothyroidism and euthyroid controls from the same population of elderly Japanese. We also sought associations of selected parameters with the development of overt hypoth...

OBJECTIVE To review the etiology, precipitating factors, clinical findings, screening recommendations, and treatment for primary hypothyroidism and subclinical hypothyroidism in the older patient. DATA SOURCES A PubMed search of English language articles using a combination of words: elderly, thyroid, hypothyroid,* subclinical hypothyroid,* etiology, screening, diagnosis, and treatment to ide...