نتایج جستجو برای: hypoxia inducible factors

تعداد نتایج: 1159240  

2017
Veronika Bäcker Fung-Yi Cheung Jens T Siveke Joachim Fandrey Sandra Winning

Inflammation and hypoxia are hallmarks of inflammatory bowel disease. Low oxygen levels activate hypoxia-inducible factors as central transcriptional regulators of cellular responses to hypoxia, particularly in myeloid cells where hypoxia-inducible factors control immune cell function and survival. Still, the role of myeloid hypoxia-inducible factor-1 during inflammatory bowel disease remains p...

Journal: :Biomedical Research and Therapy 2022

The metabolic process of normal cells in general and cancer particular requires an important molecule—oxygen. In tumors, the oxygen level tends to decrease gradually from outer layers central core, leading a condition termed ``hypoxia.'' Changes modify signaling pathways activities cells. Basically, tumor development is divided into three stages: initiation, promotion, progression. Among them, ...

Journal: :British Journal of Cancer 2010

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