INTRODUCTION The use of patient reported outcome measures to support routine inflammatory bowel disease (IBD) care is not widespread and suggests that existing questionnaires lack relevance to day-to-day decisions or are too cumbersome to administer. We developed a simple, generic tool for capturing disease control from the patient's perspective to address these barriers. METHODS Development ...

UM Women with inflammatory bowel disease (IBD) have more complications during pregnancy than women without IBD, regardless of whether the disease is active or inactive. Women with inactive IBD have more preterm births and more complications during labor and delivery than women without IBD. Disease severity also affects outcomes; preterm births were approximately 3 times more common among women ...

Although inflammatory bowel disease (IBD) rarely arises in the setting of solid organ transplantation, IBD has a higher incidence in this setting than in the general population and poses challenging management issues. The most common association is hepatic orthotopic transplant for primary sclerosing cholangitis. This article discusses IBD in the setting of liver transplantation, including both...

Inflammatory bowel disease (IBD) encompasses two illnesses Crohn’s disease (CD) and ulcerative colitis (UC) that are characterized by chronic intestinal inflammation. The disease progression of IBD is heterogeneous, as is the response of individual patients to different treatments. Typically IBD and the resultant inflammation cause a combination of abdominal pain, diarrhea, intestinal bleeding,...

Background: Inflammatory bowel disease (IBD) involves chronic inflammation of the digestive tract. In the past decades, fecal calprotectin has been proposed as a useful biomarker for the differential diagnosis between IBD patients and healthy controls. We designed this study to evaluate the diagnostic ability of fecal calprotectin (FC) and conventional inflammatory markers in IBD patients. M...

UNLABELLED We present a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. Our method builds on a recent demographic inference method based on the coalescent with recombination, and is able to incorporate demographic information as a prior. Simulation study shows that diCal-IBD has significantly higher recall and precision than that of existing s...

INTRODUCTION The best care setting for patients with inflammatory bowel disease [IBD] may be in a dedicated unit. Whereas not all gastroenterology units have the same resources to develop dedicated IBD facilities and services, there are steps that can be taken by any unit to optimise patients' access to interdisciplinary expert care. A series of pragmatic recommendations relating to IBD unit op...

Inflammatory bowel disease (IBD) is considered to be the most common cause of vomiting and diarrhoea in dogs, and the German shepherd dog (GSD) is particularly susceptible. The exact aetiology of IBD is unknown, however associations have been identified between specific single-nucleotide polymorphisms (SNPs) in Toll-like receptors (TLRs) and human IBD. However, to date, no genetic studies have ...

Inflammatory bowel disease (IBD) is a complex, multifactorial, chronic inflammatory disorder of the gastrointestinal tract in which immune dysregulation caused by genetic and/or environmental factors plays an important role. The aim of this case-control study was to evaluate the association of tumor necrosis factor-alpha (TNF-α) (308) and -β (+252) polymorphisms with susceptibility of IBD. A to...