Background & Aim: Vast variety of plants in various regions of the country and lack of enough information on their chemical combinations, sometimes lead to triggering poisoning and unsatisfied complications. Regarding to fabulous herbal characteristics of Hypricum, many research about poisoning and side effects of high concentrations of H. scabrum have not taken place...

HPD has been described in ≃14-26% of pretreated NSCLC pts upon single-agent (SA) ICI and not reported PCT-ICI. So far, no predictive biomarkers are available for early detection. treated with 1st line SA-ICI or PCT-ICI were assessed circulating neutrophils. required 3 radiological scans was defined as delta tumor growth rate (TGR) [TGR – TGR prior ICI) >50% and/or ratio (TGR ICI/ ≥2. Circulatin...

BACKGROUND African swine fever virus (ASFV) is the causative agent of African swine fever (ASF) that is the significant disease of domestic pigs. Several studies showed that ASFV can influence on porcine blood cells in vitro. Thus, we asked ourselves whether ASFV infection results in changes in porcine blood cells in vivo. A series of experiments were performed in order to investigate the effec...

in vitro maturation (ivm) is a method that immature oocytes in antral follicles are extracted and matured in laboratry conditions. this review has attempted to provide the current knowledge and recent findings in in vitro maturation of oocytes and highlights the most important factors involved in this process. the review is based on literature reports and the author’s experience. in ivm cycles,...

Background: The pathophysiology of COVID-19 disease is not clearly understood; inflammation has been shown to play a major role. immature granulocytes count (IGC) can be an indicator inflammation. To the best our knowledge, there no data on usability IGC for diagnosis COVID-19. Objectives: We aim investigate inflammatory marker in Patients and Methods: patients admitted tertiary university hosp...

background: leishmaniasis is a worldwide disease prevalent in tropical and sub- tropical countries in the world. characterization of inflammatory responses produced in cutaneous leishmaniasis has not yet been completed. methods: the specific primers were designed for ten pro-inflammatory genes including ccl4, ccl3, tnf-α, il-1α, il-12p35, il-12p40, ccl5, ccr5, il-1β and ifn- γ and their express...

The aim of the present study was to investigate the characteristics of the four subtypes of myelodysplastic/myeloproliferative neoplasms (MDS/MPNs) in order to improve current knowledge and to aid their diagnosis. A total of 53 cases of MDS/MPNs were analyzed using routine blood cell analysis and morphological, cytogenetic and molecular genetic characteristics were investigated. Numerical data ...

The quantitative changes of the high mobility group (HMG) nonhistone chromosomal proteins in nondividing, differentiated peritoneal exudate neutrophils were identified by their solubility, electrophoretic mobility on both SDS and acetic acid gels, densitometric traces and elution profile on CM-sephadex. The results indicated that in neutrophils, HMGl undergoes a considerable reduction (80%...

During systemic inflammation different neutrophil subsets are mobilized to the peripheral blood. These neutrophil subsets can be distinguished from normal circulating neutrophils (CD16/CD62L), based on either an immature CD16/ CD62L or a CD16/CD62L phenotype. Interestingly, the latter neutrophil subset is known to suppress lymphocyte proliferation ex vivo, but how neutrophils become suppressive...