background: during the initial phase of an infection, there is an upregulation of inducible nitric oxide synthase in the macrophages for the production of nitric oxide. this is followed by the recruitment of polymorphonuclear leukocytes (neutrophils) which release arginase. arginase competes with inducible nitric oxide synthase for a common substrate l-arginine. objective: to investigate whethe...

OBJECTIVE To study the effect of sepsis on circulating neutrophils in very low birth weight neonates and to assess the usefulness of recently revised reference ranges for circulating neutrophils in the diagnosis of sepsis in this population by comparison with previously reported reference ranges. METHODS Neutrophil parameters (absolute total neutrophils, absolute total immature neutrophils, a...

Cell regulation of Ph(+)cell proliferation and differentiation has been studied ex vivo in various chronic myeloid leukemia (CML) patients. The regulation is provided by alternation of effective stages of proliferation and maturation with inhibition of Ph(+) cell proliferation by accumulating neutrophils under apoptosis blockage. The alternation of stages consists of switching stage 1 (effectiv...

In this nested case-control study, we evaluated haematological and morphological parameters of hospitalised patients with real-time polymerase chain reaction verified COVID-19 infection compared to similar symptomatology but without infection. Seventy-four positive 228 negative were routine parameters. Severe disease was defined as death and/or need intensive care treatment. Twenty-seven 18 fur...

protection of the mammary gland against mastitis-causing pathogens is mediated by many factors in thegland and blood circulation. the professional phagocytic cells of bovine udder, polymorphonuclearneutrophils (pmn) and macrophages, comprise the first line of defense against invading mastitis pathogens.most researchers now accept that the pmn is a key factor in the cows’ defense against intrama...

to evaluate the effect of intrauterine cephapirin on treatment of endometritis 39 holstein dairy cows that affected with postpartum endometritis were selected and randomly assigned to two experimental designs. in experiment 1, 6 out of 14 cows were 25 to 30 days after parturition were treated by intrauterine oxytetracycline. another 8 cows were treated by intrauterine cephapirin (metri-care). i...

background: most studies on anabolic-androgenic steroids abuse have been done in adult rats, but few data are available to immature. objective: this study was conducted to assay the effect of nandrolone decanoate (nd) on the testis and testosterone concentration in male immature rats compare with mature ones in short and long time. materials and methods: 40 mature rats were divided into 4 group...

the laelapid mite, gaeolaelapsaculeifer (canestrini) is widespread in soil habitats and feeds on different small arthropods, fungi and nematodes. the development and fecundity of g. aculeifer feeding on rhizoglyphus echinopus (fumouze & robin) as prey was studied at eight different constant temperatures which include: 16, 17.5, 20, 22.5, 25, 27.5, 30 and 32.5 ºc, with relative humidity of 6...

In December 2006, a 95-year-old Japanese woman was transferred to our hospital for the evaluation of her leukocytosis. In September 2006, the patient was medicated for hypertension by her family physician and she was found to have leukocytopenia (2,500/mL) without abnormal cells in the peripheral blood (PB). During the middle of November, the patient’s white blood cell (WBC) count was found to ...

background & objectives: neutrophils are the most important member of granulocytes & the first line of host defence against micro-organisms. they kill micro-organisms entering the body by phagocytic activity. one of the important phases of phagocytic activity is respiratory burst which can be effected by different drugs such as cimetidine. in this study the effects of cimetidine on respiratory ...