gastric adenocarcinoma is the second leading cause of death due to cancer in the world and in advanced stages the prognosis is poor with current therapies. over-expression of her-2/neu has been seen in several cancers such as gastric cancer and its expression is associated with poor prognosis. the aim of this study is to evaluate the over-expression of her-2/neu in gastric biopsy samples of pat...

objective: breast cancer comprise approximately one third of malignant cases in women and is considered as the most common invasive condition in women at an age range of 15-54 years and as the second most prevalent cause of mortality at an age range of 55-74 years. tumor inhibiting factor p53 is a vital homeostatic regulator and its inactivation at the related gene or molecule could lead to tum...

enrofloxacin is a synthetic chemotherapeutic agent from the class of the fluoroquinolones that is widely used to treat bacterial infections. it is metabolized to ciprofloxacin in the body as active metabolite. fluoroquinolones change in the articular cartilage, especially with high doses and more than two weeks use. so, due to relatively excessive use of enrofloxacin in mammals and similarity o...

background: acute leukemias are characterized by neoplastic proliferation of hematopoietic stem cells and accumulation of blasts and immature cells in the bone marrow. we applied a selective panel of immunohistochemical markers on bone marrow trephine tissue sections and observed their utility in diagnosis and typing of acute leukemia. materials and methods: the study was done at psg institute ...

cutaneous metaplastic synovial cyst (cmsc), presents as a solitary, tender subcutaneous nodule that usually occurs at the site of previous surgery or trauma. histologically, the lesion is characterized by a cystic structure with villous-like projections that lined by metaplastic synovial tissue. the main cause remains unclear, but trauma is presumed to be a precipitating factor, as most reporte...

background and aims. vascular endothelial growth factor (vegf) and ki-67 antigen are contributing factors in this process cell proliferation and new blood vessels formation in tumor progression. this study was conducted to examine the relationship between the expression of vegf and ki-67 and gender and age of patients with oral squamous cell carcinoma (oscc). materials and methods. twenty-three...

an 11 year – old mixed female labrador was presented with two masses in trunk and neck. the tumoral masses were excised and sent for histopathological and immunohistochemical analyses. histopathological examination of masses revealed diffuse infiltration of small sized lymphoid cells in subcutaneous tissue which were intense around the blood vessels. more than 10% lymphoid cells were cd3 positi...

introduction: the aim of the present study was to evaluate the expression of fibronectin (fn) and tenascin (tn) after direct pulp capping (dpc) in dogs’ teeth with either mineral trioxide aggregate (mta), propolis or platelet-rich plasma (prp), by means of immunohistochemistry. methods and materials: a total of 48 sound molars and premolars with mature apices from four dogs, were included. the ...

background: carcinomas of the thyroid follicular epithelium are the most common cancers of the endocrine system. in the diagnosis of thyroid nodules and tumors, the gold standard is histological evaluation. in cases which have morphological overlap,immunohistochemistry is needed for differential diagnosis. the purpose of this study is to investigate the expressions of cd56,hbme?1, cytokeratin 1...