OBJECTIVE To examine spoken language outcomes in children undergoing bilateral cochlear implantation compared with matched peers undergoing unilateral implantation. DESIGN Case-control, frequency-matched, retrospective cross-sectional multicenter study. SETTING Two Belgian and 3 Dutch cochlear implantation centers. PARTICIPANTS Twenty-five children with 1 cochlear implant matched with 25 ...

BACKGROUND Delayed implantation is a developmental arrest at the blastocyst stage and a good model for embryo implantation. MicroRNAs (miRNAs) have been shown to be involved in mouse embryo implantation through regulating uterine gene expression. This study was to have an integrative analysis on global miRNA and mRNA expression in mouse uterus under delayed implantation and activation through I...

The success of implantation is an interactive process between the blastocyst and the uterus. Synchronized development of embryos with uterine differentiation to a receptive state is necessary to complete pregnancy. The period of uterine receptivity for implantation is limited and referred to as the "implantation window", which is regulated by ovarian steroid hormones. Implantation process is co...

BACKGROUND Autologous chondrocyte implantation (ACI) is an important procedure when repairing cartilage defects of the knee. We previously reported several basic studies on tissue-engineered cartilage, and conducted a multicenter clinical study in 2009. In this clinical study, we evaluated the patients' clinical scores and MRI findings before and after tissue-engineered cartilage implantation, ...

BACKGROUND Recent reports demonstrate that intracoronary radiation affects not only neointimal formation but also vascular remodeling. Radioactive stents and catheter-based techniques deliver radiation in different ways, suggesting that different patterns of remodeling after each technique may be expected. METHODS AND RESULTS We analyzed remodeling in 18 patients after conventional stent impl...

INTRODUCTION Glaucoma is a known complication of uveitis, and may require glaucoma tube shunt implantation for intraocular pressure (IOP) control. The success of glaucoma tube shunt implantation in the setting of a local ocular steroid depot in uveitic glaucoma remains unknown. The purpose of this study was to determine whether patients who underwent combined glaucoma tube shunt (Ahmed) and flu...

P.Borkowski, K.Skalski, W.Woźniak 1 Bialystok University of Technology, Faculty of Mechanical Engineering, Department of Materials and Biomedical Engineering; Poland, 15-351 Bialystok, ul.Wiejska 45a; [email protected] 2 Warsaw University of Technology, Faculty of Production Engineering, Department of Machine Designed and Biomedical Engineering; Poland, 02-524 Warsaw, ul.Narbutta 85 3 Institu...

The implantation process is complex, requiring reciprocal interactions between implantation-competent blastocysts and the receptive uterus. Because microRNAs (miRNAs) have major roles in regulating gene expression, we speculated that they participate in directing the highly regulated spatiotemporally expressed genetic network during implantation. Here, we show that two miRNAs, mmu-miR-101a and ...