Innovation in healthcare delivery and Pharma requires rethinking old problems, retooling with new methodologies and revisiting the process models that are foundations of our existing knowledge discovery and clinical practice. The continuing proliferation of ubiquitous sensor data, mobile devices and the advent of 3D printing of drugs, together with a social mind shift in data ownership are clea...

The standard big bang cosmological model and the history of the early universe according to the grand unified theories of strong, weak and electromagnetic interactions are summarized. The shortcomings of big bang are discussed together with their resolution by inflationary cosmology. Inflation and the subsequent oscillation and decay of the inflaton field are studied. The density perturbations ...

With the emergence of the big data concept, the big graph database model has become very popular since it provides strong modeling for complex applications and fast querying, especially for the cases that require costly join operations in RDBMs. However, it is a big challenge to find all exact matches of a query graph in a big graph database, which is known as the subgraph isomorphism problem. ...

We constrain the lifetime of thermally produced heavy neutral leptons (HNLs) from big bang nucleosynthesis. show that even a small fraction mesons present in primeval plasma leads to overproduction primordial helium-4. This constrains HNLs be ${\ensuremath{\tau}}_{N}<0.02\text{ }\text{ }\mathrm{s}$ for masses above mass pion (as compared 0.1 s reported previously). In combination with accele...

Plant identification and classification are critical to understand, protect, conserve biodiversity. Traditional plant requires years of intensive training experience, making it difficult for others classify plants. leaf is a challenging issue as similar features appears in different species plant. With the development automated image-based classification, machine learning (ML) becoming very pop...

We describe a class of holographic models that may the physics certain four-dimensional big-bang / big-crunch cosmologies. The construction involves pair 3D Euclidean CFTs each on homogeneous and isotropic space $M$ coupled at either end an interval ${\cal I}$ to 4D CFT $M \times {\cal with many fewer local degrees freedom. argue in some cases, when size is much greater than length I}$, theory ...

Since the idea of Bulgaria joining NATO was launched in public space, the debate has targeted predominantly the political and the military-technical aspects of the issue. The Employers Association of Bulgaria does not underestimate the importance of these factors nonetheless, as a representative of the big domestic private capital, we believe that it is about time to seriously and extensively r...

It has become widely accepted that temporal asymmetry is largely a cosmological problem; the task of explaining temporal asymmetry reduces in the main to that of explaining an aspect of the condition of the early universe. However, cosmologists who discuss these issues often make mistakes similar to those that plagued nineteenth century discussions of the statistical foundations of thermodynami...