Background—Genes and mechanisms of action involved in human acute rejection after allogeneic heart transplantation remain to be elucidated. The use of a murine allograft model in tandem with cDNA arrays and quantitative real-time polymerase chain reaction (Q-PCR) can greatly help in identifying key genes implicated in human heart acute rejection. Methods and Results—Hearts from Balb/c mice were...

Human red blood cells (RBCs) have remarkable deformability, squeezing through narrow capillaries as small as three microns in diameter without any damage. Several pathological conditions, including malaria, sickle cell disease (SCD), and diabetes can alter the shape and deformability of circulating RBCs. Recent work demonstrates how new computational and analytical models can reveal the ways in...

UNLABELLED We developed a CGI/Perl-based web server to perform in silico polymerase chain reaction (PCR) on PCR primer sequences. The PUNS (Primer-UniGene Selectivity) server simulates PCR reactions by running BLASTN analysis on user-entered primer pairs against both the transcriptome and the genome to assess primer specificity. PUNS is particularly suited for the identification of highly selec...

We have systematically studied the evolution of the photoluminescence(PL) tuning of porous silicon(PS) by electrochemical etching in various mixed electrolytes. The electrolytes employed as an etchants were mixtures of HF:CH3COOH:HNO3:C2H5OH solutions where the composition ratios (%) were varied from 10:1.98:0:88.02 to 10:1.98:8.4:79.62 under constant concentration of HF and CH3COOH with a tota...

1 Department of Forensic Medicine and Veterinary Toxicology, Faculty of Veterinary Medicine, South Valley University, 83523 Qena-Egypt 2 Department of Medical Laboratories, Collage of Applied Medical Sciences, Majmaah University-Kingdom of Saudi Arabia 3 Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Hacettepe University, Sıhyyie/Ankara-Türkiye 4 Division of Cerebral Circuitry, N...

Malaria, one of the most widespread diseases, is caused by a plasmodium parasite million people each year, results in several million deaths annually. protozoa that cause malaria, no one antimalarial drug is effective against all four species. research investigation, we performed antimalarial agents. To design a new molecule having good pha information. Key-words: TPSA, GPCR, ADMETox, Malaria i...

Cell walls are of interest to plant biochemists and cell biologists for two main reasons: they regulate cellular morphogenesis and act as structural support materials. As it is a major component of plant cell walls and a natural product of considerable commercial value, cellulose has long been a focus of interest in cell-wall biology, although it is far from the only constituent of cell walls. ...