objective(s) indigofera tinctoria linn. of fabaceae family is claimed to be useful to control epileptic seizures in the indian system of folkore medicine. this study was designed to evaluate i. tinctoria and to verify the claim. materials and methods seizures were induced in male albino rats with pentylenetetrazole (ptz). the test group animals were administered ethanolic extract of indigofera ...

Background and Purpose: This research aimed to investigate the in vivo acute oral toxicity of aqueous extract of Indigofera tinctoria L. in different doses in Wistar rats. Materials and Methods: Twenty-five male rats were divided into five groups (n=5 for each group). Group I served as the control, and the other four groups received I. tinctoria (100, 250, 500, and 1000mg/kg body weight) for 1...

Cisplatin is widely used chemotherapeutic agent for the treatment of several human malignancies. The efficacy is dose dependent, but the significant risk of nephrotoxicity frequently inhibits the use of higher doses to maximize its anti-neoplastic effects. In the present investigation, the Avuri kudineer [Decoction of Indigofera tinctoria] made of indigo leaves AKL, the Avuri kudineer made of i...

Chronic myelogenous leukemia (CML) is a slowly progressive disease characterized by the overproduction of granulocytes (neutrophils, eosinophils, and basophils). A blood smear shows moderate elevations in white blood cell counts that may persist for years and be benign. Platelets are increased in number, although their function is impaired, resulting in symptoms of easy bleeding (purpura, swoll...

The seeds of Indigofera heterantha yielded a flavonoid characterized as quercetin 3-O-α-L-rhamnoside along with known 3,5,7-trihydroxy-6,4 ́-dimethoxyflavone and 3,5,4 ́-trihydroxy-6,7-dimethoxyflavone. The isolated compounds were characterized by using modern spectroscopic techniques such as UV, IR, NMR and mass.

Chronic myelagenous leukemia (CML) is a slowly progressive disease characterized by the overproduction of granulocytes (neutrophils, eosinophils and basophils). A blood smear shows moderate elevations in white blood cell counts that may persist for years and be benign. Platelets are increased in number although their function is impaired, resulting in symptoms of easy bleeding (purpura, swollen...

Indigofera tinctoria and Scoparia dulcis are being widely used in Indian folk medicine for the treatment of various disorders. Environmental noise pollution is thought to be an important factor for many health problems and it causes immune abnormalities. In the present study immune-regulating potential of I. tinctoria and S. dulcis aqueous extracts on innate and adaptive immune system of wistar...

The objective of this study was to evaluate the free radical scavenging potential and high performance thin layer chromatography (HPTLC) fingerprinting of Indigofera tinctoria (I. tinctoria). Phytochemical analysis was carried out using standard methods, and free radical scavenging activity of the plant was determined using 2,2-diphenyl-1-picrylhydrazy (DPPH), nitric oxide (NO) and superoxide a...

Six rotenoids have isolated from Indigofera tinctoria, characterized by means of their spectral data and/or co-tlc. The total estimation studies revealed that rotenol was major rotenoid in both in vivo and in vitro. Similarly, by elicitation studies, we observed that summatrol synthesis was higher at the concentration of 0.01 mM ergosterol and salicylic acid. Among all sequential fractions, met...