نتایج جستجو برای: indoline
تعداد نتایج: 604 فیلتر نتایج به سال:
A simple and efficient method for the synthesis of spiro[indoline-3,9'-xanthene]trione derivatives by means of condensation between isatins and 1,3-cyclohexanedione in the presence of a catalytic amount of magnesium perchlorate at 80 °C in 50% aqueous ethanol medium has been described. Notably, the present method offers desirable advantages of good yields, simplicity of workup procedure, easy p...
The indoline fused-ring system of the title Schiff base, C(14)H(11)N(3)O, is planar (r.m.s. deviation = 0.005 Å); the phenyl substituent is aligned at 66.5 (1)° with respect to the ring system. The amino -NH(2) unit forms an intra-molecular hydrogen bond with the carbonyl O atom. Mol-ecules are connected by an inter-molecular N-H⋯N hydrogen bond, generating a zigzag chain that runs along the sh...
A practical and green method for the synthesis of 5H-dibenzo[b,i]xanthene-tetraones and spiro[dibenzo[b,i]xanthene-13,3'-indoline]-pentaones by the condensation of 2-hydroxynaphthalene-1,4-dione with aldehydes or isatins, respectively, in the presence of a catalytic amount of cellulose sulfuric acid (CSA) under solvent-free conditions at 100 °C is described. The significant features of this pro...
tention as a promising drug candidate for anticoagulation. FXa, a serine protease in the blood coagulation cascade, is essential for the formation of thrombin. It plays an important role in the coagulation cascade at the convergent point of the intrinsic and the extrinsic pathway. FXa inhibitor is expected to be a novel antithrombotic with potential for the treatment and prevention of thromboem...
In the title compound, C(23)H(19)N(3)O(4), the pyran ring adopts a half-chair conformation, while the pyrrolidine (with a C atom as the flap atom) and the five-membered ring in the indoline (with a C atom as the flap atom) ring system adopt slight envelope conformations. The pyrrolidine ring makes dihedral angles of 83.3 (1) and 60.4 (1)° with the mean plane through all non-H atoms of the indol...
Advances in solar cell technology require designing of new organic dye sensitizers for dye-sensitized solar cells with high power conversion efficiency to circumvent the disadvantages of silicon-based solar cells. In silico studies including quantitative structureproperty relationship analysis combined with quantum chemical analysis were employed to understand the primary electron transfer mech...
Five new spiro[indoline-3,3′-indolizine]s have been synthesized with high regio- and stereospecificity in one-pot three-component reactions between a substituted indole-2,3-dione, ( S )-pipecolic acid trans -3-benzoylacrylic acid, subsequently characterized using combination of elemental analysis, IR 1 H 13 C NMR spectroscopy, mass spectrometry crystal structure analysis. (1′ SR ,2′ ,3 RS ,8a′ ...
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