نتایج جستجو برای: indoline
تعداد نتایج: 604 فیلتر نتایج به سال:
Benzocyclobutenes (BCBs) are of growing interest in materials and medicinal chemistry, although general routes for their provision remain underexplored. A modular, divergent, stereoselective Cu- Pd-catalyzed assembly/cyclization sequence allows the synthesis densely functionalized BCBs, from readily accessible imine, allene, diboron precursors. Preliminary results have identified enantioselecti...
A simple catalytic protocol for the synthesis of novel spiro[indoline-pyranodioxine] derivatives has been developed using ZnO nanoparticle as an efficient, green, and reusable catalyst. The derivatives are obtained in moderate to excellent yield by one-pot three-component reaction of an isatin, malononitrile/ethylcyanoacetate, and 2,2-dimethyl-1,3-dioxane-4,6-dione in absolute ethanol under con...
The inhibiting effect of nitrogen compounds on the hydrogenation of aromatic compounds and on the hydrodesulphurization (HDS) of dibenzothiophene (DBT) and 4,6-dimethyl dibenzothiophene (4,6 DMDBT), has been systematically investigated over a commercial NiMo hydrotreating catalyst. Amongst the different nitrogen compounds considered, interestingly ammonia was found to have the strongest inhibit...
The compound 1-(2,6-dichlorophenyl)indolin-2-one (1), planned as a pro-drug of diclofenac (2), was easily synthesized in 94% yield by an intramolecular reaction in the presence of coupling agent (i.e., EDC). Compound 1 showed anti-inflammatory and analgesic activity without gastro-ulcerogenic effects. The chemical and enzymatic hydrolysis profile of the lactam derivative 1 does not indicate con...
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