the harmful use of alcohol inflicts great deal of social and economic losses on individuals and societies. given the increase in world population and the predicted increase in alcohol consumption, the alcohol related burden of disease progressively catches higher ranks in the list of factors threatening humans' life. it has been considered that the social and economic burden related to alcohol ...

alcohol provokes different molecular pathways contributing to a clinically significant neurotoxicity in different brain areas. affected cognition in alcoholics can influence both daily life functioning and alcohol craving management abilities. preventing alcohol-induced neurotoxicity with different neuroprotective pharmacological interventions is receiving strong scientific backgrounds from pub...

in the present study, the effects of intracerebroventricular (icv) administration of normal saline (control), histamine, mepyramine (a histamine h1-receptor antagonist) and ranitidine (a histamine h2-receptor antagonist) were investigated on the formalin-induced pain in rabbits. subcutaneous (sc) injection of a formalin (100 μl, 5%) solution into the ventral surface of the right hind paw was pe...

background: cirrhotic patients are at a greater risk of different kinds of arrhythmias. despite the well-known arrhythmogenic effects of halothane, developing countries continue to use halothane due to its low cost. this study was designed to investigate the pathophysiology of halothane untoward effects on heart rhythm moreover was aimed to explore the effect of halothane anesthesia on the thre...

echium amoenum is an iranian indigenous medicinal plant. in this research the effect of hydroalchoholic extract of this plant on sodium-selenite induced cataract formation was evaluated. fifty five white rat pups were selected and divided into six groups. in first group (control 1) no elements injected. second group (control 2) was received normal saline on 11-18 postpartum. hydroalchoholic ext...

background: the term caustic generally refers to alkaline and the term corrosive generally refers to acidic agents' injury however, in medical literature caustic is frequently a term applied to both substances. ingested alkali typically damage the esophagus more than stomach or duodenum, whereas acids usually cause more severe gastric injury. since esophagus has a slightly alkaline ph, its...

abstract background: the incidence of pregnancy induced hypertension (pih) which is one of the three main causes of maternal-neonatal morbidity and mortality is 5-7%, and prediction of this disorder is very important in maternal and neonatal health. methods: the type of this study is analytical (comparative-prospective) and its purpose is to evaluate the isometric exercise test (let) and roll-o...

objectives: this study aimed to compare the combination of cimt and bim training with cimt in fine motor skills of children with hemiplegic cerebral palsy. methods: 24 children with hemiplegic cerebral palsy aged between 60 and 120 months participated in this rct study. they were randomly assigned into cimt and bim training (n=12, four males, eight females mean age±standard deviation=93.58±14.2...

conclusions results showed that the boiled anethum graveolens seeds was effective on labor induction. results case group had a significantly better bishop score following the intervention compared to the control group. the mean duration of active phase, second and third stages of labor were significantly lower in the case group. the control group had shorter latent phase than the case group. pa...

this study aimed to investigate the potency of silymarin (smn) and melatonin (mel) on restoring the pancreatic  cells in streptozotocin (stz)-induced diabetic rats. male wistar rats were divided into five groups, including: control (c), untreated diabetic (d), smn-treated diabetic (50 mg/kg, orally), mel-treated diabetic (10 mg/kg, i.p.), and smn plus mel-treated diabetic rats. diabetes was in...