Half of the severe asthma patients suffer from uncontrolled exacerbations. Our work in neuro-immunology has shown that, context asthma, vagal nociceptor neurons drive a feed-forward inflammatory loop with lung immune cells, and that silencing these reverses allergic airway inflammation (AAI). Here, we aim to expand findings clinically relevant model pollution exacerbated asthma. Experimental al...

Small and medium extracellular vesicles, identified characterised in exhaled breath condensate induced sputum supernatants, might provide pathophysiological insights novel biomarkers severe asthma COPD patientshttps://bit.ly/3fiTnXY

ATS/ERS statement: asthma control and exacerbations 2 Consistently very poorly controlled asthma increases risk for future severe asthma exacerbations 2 The FDA and safe use of long-acting beta-agonists in the treatment of asthma 2 Thirteen-year follow-up of early intervention with an inhaled corticosteroid in patients with asthma 3 Oral prednisolone for preschool children with acute virus-indu...