ziziphora tenuior is one of the traditional medicinal herbs; the main active chemical composition of this herb is an ingredient named as pulegone which is known well for its anti-inflammatory and analgesic effects. considering, the side effects of synthetic drugs, researcher’s attention has been attracted to the use of herbal medicines.in this study, after inducing ear edema via xylenol, the an...

this study investigated the presence of mast cells in inflammatory aural polyps using light microscopy. the number of mast cells was increased in all examined cases and varied from 2.33 to 41.54 per mm2• the cells were located most commonly around small blood vessels. occurrence of mast cells was not different in various types of polyps, but their density was severely increased in active inflam...

objective: this study was aimed to examine the antinociceptive and anti-inflammatory effects of urtica dioica leaf extract in animal models. materials and methods: hydroalcoholic extract of the plant leaves was prepared by percolation method. male swiss mice (25-35 g) and male wistar rats (180-200 g) were randomly distributed in control, standard drug, and three experimental groups (n=6 in each...

background & aim:zea mays leaf used traditionally in ibibio ethno medicine in southern nigeria to treat malaria and other inflammatory diseases. these anti-inflammatory and analgesic properties were evaluated against experimentally induced inflammation and pains using standard models. experimental: the effects of ethanol leaf extract of zea mays (170 -510 mg/kg) on experimentally induced inflam...

a new series of transition metal complexes of co(ii), ni(ii), cu(ii) and zn(ii), has beensynthesized from the knoevenagel condensate schiff base ligand(l) derived from β-ketoanilideand furfural with o-phenylenediamine and diethylmalonate. structural features were determinedby spectral and analytical techniques. square-planar geometry has been adopted by thecomplexes except cobalt complex which ...

licorice, the oldest chinese traditional medicine, is widely used in the treatment of human diseases. due to the deficiency of wild resource, selecting and breeding becomes a key issue to expanding the supply of licorice. spaceflight technology will become a new method for medicinal plants. the aim of this study was to investigate the effect of spaceflight on the components and anti-inflammator...

fibrates, as hypolipidemic drugs known as agonists of peroxisome proliferator-activated receptors, diminish inflammatory responses. studies have shown that incorporation of a silicon atom into a drug structure improves its pharmacological potency, modifies its selectivity toward a given target, or changes its metabolic rate, in addition to increasing the lipophilicity of the compounds. a silico...

introduction: dark neurons which their morphological characteristics are consistent with those of cells undergoing apoptosis, are generated as an acute or delayed consequence of several pathological situations. the present study was designed to evaluate whether inflammatory pain regarding the role of no and jnk lead to the formation of dark neurons in the dorsal horn of the lumbar spinal cord i...

the inflammatory bowel diseases (ibd) have been found to accompany some neurological syndromes including multiple sclerosis (ms). recently, several studies have reported and discussed the simultaneous presence of ibd and ms in some patients. thus, in patients with either disease, the presence of signs and symptoms of the other should raise the clinical suspicion of the clinician and warrant spe...

roaccutaneâ® (isotretinoin) is used for the treatment of severe forms of acne resistant to adequate standard therapy. inflammatory bowel disease (ibd) is described as a possible adverse drug reaction in the product information of isotretinoin. in a case study, we report the case of a 30 year old woman with a history of bloody diarrhea, abdominal pain and severe folliculitis/acne which had been ...