the aim of the present work was to prepare and characterize biopolymer nanocarriers and evaluate their suitability in possible oral delivery of insulin. the egg albumin biopolymer was used to prepare nanoparticles which were further characterized by fourier transformed infrared spectroscopy (ftir), transmission electron microscopy (tem), scanning electron microscopy (sem), zeta potential, dynam...

background: in this study, we aim to compare insulin and leptin levels in adolescents with or without overweight and in those with or without abdominal obesity. materials and methods: this case-control study was conducted among 486 samples. we randomly selected 243 overweight and an equal number of normal-weight adolescents from among participants of the third survey of a national surveillance ...

background: obesity has emerged as one of the most serious public health concerns in the 21st century. the consequences of this chronic disorder are serious. bariatric surgery has been shown to eliminate comorbid conditions associated with obesity. currently it is considered to be the only successful, long-term therapy for morbidly obese subjects.rnobjectives: the aim of this study was to evalu...

context turmeric is obtained from the plant curcuma longa l; its major constituent, curcumin, is a polyphenol with multiple effects which can modulate some signaling pathways. evidence acquisition insulin resistance is a major risk factor for chronic diseases such as type 2 diabetes, atherosclerotic, metabolic syndrome and cardiovascular disease. in addition, insulin resistance in peripheral ti...

introduction: oral delivery is the most favorable route for insulin administration. the aim of this study was to generate new chitosan coated insulin nanoliposomes and then to assess the physiological efficacy of these nanoliposomes after oral administration in diabetic rabbits. methods: nanoliposomes with negative surface charge encapsulating insulin were prepared by reverse phase evaporation ...

background: polycystic ovary syndrome (pcos) is a complex disease having both genetic and environmental components and candidate genes on obesity and insulin metabolism have been hypothesized to be involved in its etiology. objective: we examined the possible association of adiponectin and insulin receptor gene polymorphisms with pcos. materials and methods: a total of 186 women with pcos using...

hyperglycemia and gestational diabetes mellitus are complications of pregnancy. both mothers and newborns are typically at increased risk for complications. this study sought to determine effect of zinc supplementation on serum glucose levels, insulin resistance, energy and macronutrients intakes in pregnant women with impaired glucose tolerance.in this clinical trial 44 pregnant women with imp...

Insulin resistance as a hallmark of type 2 DM (T2DM) plays role in dementia by promoting pathological lesions or enhancing the vulnerability brain. Numerous studies related to insulin/insulin-like growth factor 1 (IGF-1) signaling are linked with various types dementia. Brain insulin is disturbances Aβ production and clearance, Tau hyperphosphorylation, microglial activation causing increased n...