abstract bckground: patients with obstructive sleep apnea (osa) are at risk of developing the fatty liver as a result of being overweight. several studies suggest that osa per se could be a risk factor for liver injury and ischemic hepatitis with osa. the osa is an independent risk factor for insulin resistance. therefore, we investigated liver enzymes and insulin resistance in patients with os...

conclusions vitamin d repletion for 12 weeks increased serum vitamin d concentrations and improved β-cell activity in vitamin d-deficient type ii diabetes with no significant changes in hba1c or insulin sensitivity. results median [iqr] 25(oh)d levels increased significantly in the vitamin d group as 58.1 [48, 67.3] nmol/l (p = 0.002). there was no significant difference in the change of hba1c ...

background limited data are available regarding the effects of combined administration of cumin cyminum l. and lime on weight loss and metabolic profiles among subjects with overweight subjects. objectives the current study aimed to assess the effects of combined administration of cumin cyminum l. and lime on weight loss and metabolic profiles among subjects with overweight. patients and method...

conclusions therapeutic dose of vitamin d can improve vitamin d status and glycemic indicators. but it seems that an 8-week intervention period was not sufficient to reveal the possible effects of vitamin d on serum adiponectin levels. results after 8-week intervention, serum 25-hydroxyvitamin d significantly increased and reached the normal levels in patients receiving vitamin d (p < 0.001) an...

Objective: Obesity is a factor in the development of insulin resistance and type 2 diabetes. Obesity contributes a wide variety of metabolic changes such as insulin resistance. The insulin signal mechanism to intra-cells occurs in insulin resistance, primarily in adipose tissue cells, which can be appropriate targets for therapeutic approaches by recognizing the proteins in this pathway. The st...

background: s-methyl cysteine (smc) is a hydrophilic cysteine-containing compound naturally found in garlic and onion. the purpose of the present study was to investigate the protective effect of smc on oxidative stress, inflammation and insulin resistance in an experiment of metabolic syndrome. methods: male wistar rats were divided into five groups (6 rats in each group), namely; control, con...

background reversibility of advanced fibrosis after hcv-clearance is an important goal of therapy. objectives measuring liver stiffness (ls) by transient elastography (te) might be helpful in this setting. patients and methods we evaluated 104 patients with biopsy-proven chronic hepatitis c (chc) and sustained virological response (svr) after peg-interferon (ifn) plus ribavirin since at least 1...

conclusions: prevalence of fatty liver is high in our obese children. it was associated with criteria of metabolic syndrome and insulin resistance, so visceral fat may participate in the pathogenesis of the metabolic syndrome or merely serve as a marker of increased risk for the metabolic complications of obesity. patients and methods: 102 obese iranian children, referred to pediatric clinics f...